rs80357961

minus

Geno	Mag	Summary
(-;TCTCA)	6	BRCA1 variant considered pathogenic for breast cancer
(TCTCA;TCTCA)	0	common in clinvar

Make rs80357961(-;-)

Reference

GRCh38 38.1/141

Chromosome

17

Position

43092661

Gene

BRCA1

is a	snp
is	mentioned by
dbSNP	rs80357961
dbSNP (classic)	rs80357961
ClinGen	rs80357961
ebi	rs80357961
HLI	rs80357961
Exac	rs80357961
Gnomad	rs80357961
Varsome	rs80357961
LitVar	rs80357961
Map	rs80357961
PheGenI	rs80357961
Biobank	rs80357961
1000 genomes	rs80357961
hgdp	rs80357961
ensembl	rs80357961
geneview	rs80357961
scholar	rs80357961
google	rs80357961
pharmgkb	rs80357961
gwascentral	rs80357961
openSNP	rs80357961
23andMe	rs80357961
SNPshot	rs80357961
SNPdbe	rs80357961
MSV3d	rs80357961
GWAS Ctlg	rs80357961

Status

Merged into rs80357819

Max Magnitude

6

rs80357961, also known as 2985del5, c.2866_2870delTCTCA and p.Ser956_Gln957?fs, is a variant in the BRCA1 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk
Alt
Reference	Rs80357961(TCTCA;TCTCA)
Significance	Pathogenic
Disease	not provided Breast-ovarian cancer Hereditary breast and ovarian cancer syndrome Familial cancer of breast
Variation	info
Gene	BRCA1
CLNDBN	not provided Breast-ovarian cancer, familial 1 Hereditary breast and ovarian cancer syndrome Familial cancer of breast
Reversed	1
HGVS	NC_000017.10:g.41244678_41244682delTGAGA
CLNSRC	Breast Cancer Information Core (BRCA1)
CLNACC	RCV000047993.5, RCV000111951.4, RCV000195360.1, RCV000239021.1,