rs80358883

Orientation

plus

Stabilized

plus

Geno	Mag	Summary
(G;T)	6	BRCA2 variant considered pathogenic for breast cancer
(T;T)	0	common in clinvar

Make rs80358883(G;G)

Reference

GRCh38 38.1/141

Chromosome

13

Position

32340817

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80358883
dbSNP (classic)	rs80358883
ClinGen	rs80358883
ebi	rs80358883
HLI	rs80358883
Exac	rs80358883
Gnomad	rs80358883
Varsome	rs80358883
LitVar	rs80358883
Map	rs80358883
PheGenI	rs80358883
Biobank	rs80358883
1000 genomes	rs80358883
hgdp	rs80358883
ensembl	rs80358883
geneview	rs80358883
scholar	rs80358883
google	rs80358883
pharmgkb	rs80358883
gwascentral	rs80358883
openSNP	rs80358883
23andMe	rs80358883
SNPshot	rs80358883
SNPdbe	rs80358883
MSV3d	rs80358883
GWAS Ctlg	rs80358883

Max Magnitude

6

rs80358883, also known as Y2154X, c.6462T>G and p.Tyr2154Ter, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80358883(G;G)
Alt	rs80358883(G;G)
Reference	Rs80358883(T;T)
Significance	Pathogenic
Disease	Familial cancer of breast Breast-ovarian cancer
Variation	info
Gene	BRCA2
CLNDBN	Familial cancer of breast Breast-ovarian cancer, familial 2
Reversed	0
HGVS	NC_000013.10:g.32914954T>G
CLNSRC	ClinVar
CLNACC	RCV000044964.2, RCV000113596.2,