rs80359446

plus

Geno	Mag	Summary
(-;TA)	6	BRCA2 variant considered pathogenic for breast cancer
(AT;AT)	0	common in clinvar
(TA;TA)	0	common in clinvar

Make rs80359446(-;-)

Reference

GRCh38 38.1/141

Chromosome

13

Position

32338764

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80359446
dbSNP (classic)	rs80359446
ClinGen	rs80359446
ebi	rs80359446
HLI	rs80359446
Exac	rs80359446
Gnomad	rs80359446
Varsome	rs80359446
LitVar	rs80359446
Map	rs80359446
PheGenI	rs80359446
Biobank	rs80359446
1000 genomes	rs80359446
hgdp	rs80359446
ensembl	rs80359446
geneview	rs80359446
scholar	rs80359446
google	rs80359446
pharmgkb	rs80359446
gwascentral	rs80359446
openSNP	rs80359446
23andMe	rs80359446
SNPshot	rs80359446
SNPdbe	rs80359446
MSV3d	rs80359446
GWAS Ctlg	rs80359446

Merged from

Rs777816486

Max Magnitude

6

rs80359446, also known as 4637delTA, c.4409_4410delTA and p.Ile1470Lysfs, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80359446(-;-) Rs80359446(AT;AT)
Alt	rs80359446(-;-) Rs80359446(AT;AT)
Reference	Rs80359446(TA;TA)
Significance	Pathogenic
Disease	Familial cancer of breast Breast-ovarian cancer
Variation	info
Gene	BRCA2
CLNDBN	Familial cancer of breast Breast-ovarian cancer, familial 2
Reversed	0
HGVS	NC_000013.10:g.32912901_32912902delTA
CLNSRC	Breast Cancer Information Core (BRCA2)
CLNACC	RCV000044406.2, RCV000113300.2,