rs80359576

plus

Geno	Mag	Summary
(-;GT)	6	BRCA2 variant considered pathogenic for breast cancer
(GT;GT)	0	common in clinvar
(TG;TG)	0	common in clinvar

Make rs80359576(-;-)

Reference

GRCh38 38.1/141

Chromosome

13

Position

32340707

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80359576
dbSNP (classic)	rs80359576
ClinGen	rs80359576
ebi	rs80359576
HLI	rs80359576
Exac	rs80359576
Gnomad	rs80359576
Varsome	rs80359576
LitVar	rs80359576
Map	rs80359576
PheGenI	rs80359576
Biobank	rs80359576
1000 genomes	rs80359576
hgdp	rs80359576
ensembl	rs80359576
geneview	rs80359576
scholar	rs80359576
google	rs80359576
pharmgkb	rs80359576
gwascentral	rs80359576
openSNP	rs80359576
23andMe	rs80359576
SNPshot	rs80359576
SNPdbe	rs80359576
MSV3d	rs80359576
GWAS Ctlg	rs80359576

Max Magnitude

6

rs80359576, also known as 6580delGT, c.6352_6353delGT and p.Val2118Lysfs, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80359576(-;-)
Alt	rs80359576(-;-)
Reference	Rs80359576(TG;TG)
Significance	Pathogenic
Disease	Hereditary breast and ovarian cancer syndrome Breast-ovarian cancer Hereditary cancer-predisposing syndrome not provided
Variation	info
Gene	BRCA2
CLNDBN	Hereditary breast and ovarian cancer syndrome Breast-ovarian cancer, familial 2 Hereditary cancer-predisposing syndrome not provided
Reversed	0
HGVS	NC_000013.10:g.32914844_32914845delGT
CLNSRC	Breast Cancer Information Core (BRCA2)
CLNACC	RCV000044921.3, RCV000113578.3, RCV000217850.1, RCV000237021.1,