rs80359876

minus

Geno	Mag	Summary
(-;CTGGCCTGACCCCAGAAGA)	6	BRCA1 variant considered pathogenic for breast cancer
(CTGGCCTGACCCCAGAAGA;CTGGCCTGACCCCAGAAGA)	0	Normal

Make rs80359876(-;-)

Reference

GRCh38 38.1/141

Chromosome

17

Position

43070932

Gene

BRCA1

is a	snp
is	mentioned by
dbSNP	rs80359876
dbSNP (classic)	rs80359876
ClinGen	rs80359876
ebi	rs80359876
HLI	rs80359876
Exac	rs80359876
Gnomad	rs80359876
Varsome	rs80359876
LitVar	rs80359876
Map	rs80359876
PheGenI	rs80359876
Biobank	rs80359876
1000 genomes	rs80359876
hgdp	rs80359876
ensembl	rs80359876
geneview	rs80359876
scholar	rs80359876
google	rs80359876
pharmgkb	rs80359876
gwascentral	rs80359876
openSNP	rs80359876
23andMe	rs80359876
SNPshot	rs80359876
SNPdbe	rs80359876
MSV3d	rs80359876
GWAS Ctlg	rs80359876

Max Magnitude

6

rs80359876, also known as 5083del19, c.4964_4982del and p.Ser1655_Glu1661?fs, is a variant in the BRCA1 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80359876(-;-)
Alt	rs80359876(-;-)
Reference	Rs80359876(CTGGCCTGACCCCAGAAGA;CTGGCCTGACCCCAGAAGA)
Significance	Pathogenic
Disease	Breast-ovarian cancer Hereditary breast and ovarian cancer syndrome Hereditary cancer-predisposing syndrome not provided Familial cancer of breast
Variation	info
Gene	BRCA1
CLNDBN	Breast-ovarian cancer, familial 1 Hereditary breast and ovarian cancer syndrome Hereditary cancer-predisposing syndrome not provided Familial cancer of breast
Reversed	1
HGVS	NC_000017.10:g.41222949_41222967del19
CLNSRC	Breast Cancer Information Core (BRCA1)
CLNACC	RCV000031197.9, RCV000123279.3, RCV000130587.3, RCV000159927.3, RCV000466904.1,