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rs921451

From SNPedia

Orientationplus
Stabilizedplus
Make rs921451(C;C)
Make rs921451(C;T)
Make rs921451(T;T)
ReferenceGRCh38 38.1/141
Chromosome7
Position50555587
GeneDDC
is asnp
is mentioned by
dbSNPrs921451
dbSNP (classic)rs921451
ClinGenrs921451
ebirs921451
HLIrs921451
Exacrs921451
Gnomadrs921451
Varsomers921451
LitVarrs921451
Maprs921451
PheGenIrs921451
Biobankrs921451
1000 genomesrs921451
hgdprs921451
ensemblrs921451
geneviewrs921451
scholarrs921451
googlers921451
pharmgkbrs921451
gwascentralrs921451
openSNPrs921451
23andMers921451
23andMe allrs921451
SNPshotrs921451
SNPdbers921451
MSV3drs921451
GWAS Ctlgrs921451
GMAF0.3384
Max Magnitude0
? (C;C) (C;T) (T;T) 28


per OMIM, Ma et al. (2005) [PMID 15879433] found two different DDC haplotypes associated with nicotine dependence in African Americans and European Americans (with measures of smoking quantity [SQ], heaviness of smoking index [HSI], and the Fagerstrom test for ND [FTND])

OMIM188890
DescTOBACCO Addiction, SUSCEPTIBILITY TO
Variant
Relatedalso
OMIM107930
DescDOPA DECARBOXYLASE; DDC
Variant
Relatedalso



[PMID 17184203] DOPA decarboxylase gene is associated with nicotine dependence.


[PMID 19184136OA-icon.png] Examination of association of genes in the serotonin system to autism.



[PMID 25805645] Polymorphism of the dopamine transporter type 1 gene modifies the treatment response in Parkinson's disease