rs9472817
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 2.1 | CC genotype increases risk of Alzheimer's in epsilon 4s. |
| (C;G) | 2.1 | CG genotype increases Alzheimer's risk relative to GG in epsilon 4s |
| (G;G) | 2.1 | Reduces risk of Alzheimer's in those with epsilon 4 |
| Reference | GRCh38.p2 38.2/146 |
| Chromosome | 6 |
| Position | 46673255 |
| Gene | LOC101926934, SLC25A27 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs9472817 |
| dbSNP (classic) | rs9472817 |
| ClinGen | rs9472817 |
| ebi | rs9472817 |
| HLI | rs9472817 |
| Exac | rs9472817 |
| Gnomad | rs9472817 |
| Varsome | rs9472817 |
| LitVar | rs9472817 |
| Map | rs9472817 |
| PheGenI | rs9472817 |
| Biobank | rs9472817 |
| 1000 genomes | rs9472817 |
| hgdp | rs9472817 |
| ensembl | rs9472817 |
| geneview | rs9472817 |
| scholar | rs9472817 |
| rs9472817 | |
| pharmgkb | rs9472817 |
| gwascentral | rs9472817 |
| openSNP | rs9472817 |
| 23andMe | rs9472817 |
| SNPshot | rs9472817 |
| SNPdbe | rs9472817 |
| MSV3d | rs9472817 |
| GWAS Ctlg | rs9472817 |
| Max Magnitude | 2.1 |
| ? | (C;C) (C;G) (G;G) | 28 |
|---|---|---|
|
| ||
Homozygote carriers of the C allele who were also carriers of epsilon 4 genotype were at increased risk of LOAD (Late onset Alzheimer's disease). However, homozygote carriers of the G allele who were also carriers of epsilon 4 genotype had their increased risk of Alzheimer's reduced [PMID 26923023].
