rs9864422

plus

Geno	Mag	Summary
(C;C)	0	normal
(C;T)		1.45x increased osteoarthritis risk
(T;T)		1.45x increased osteoarthritis risk

Reference

GRCh38 38.1/141

Chromosome

3

Position

15185745

Gene

COL6A4P1

is a	snp
is	mentioned by
dbSNP	rs9864422
dbSNP (classic)	rs9864422
ClinGen	rs9864422
ebi	rs9864422
HLI	rs9864422
Exac	rs9864422
Gnomad	rs9864422
Varsome	rs9864422
LitVar	rs9864422
Map	rs9864422
PheGenI	rs9864422
Biobank	rs9864422
1000 genomes	rs9864422
hgdp	rs9864422
ensembl	rs9864422
geneview	rs9864422
scholar	rs9864422
google	rs9864422
pharmgkb	rs9864422
gwascentral	rs9864422
openSNP	rs9864422
23andMe	rs9864422
SNPshot	rs9864422
SNPdbe	rs9864422
MSV3d	rs9864422
GWAS Ctlg	rs9864422

GMAF

0.247

Max Magnitude

0

?

(C;C) (C;T) (T;T)

28

rs9864422 is one of several SNPs in the DVWA gene found to be associated with osteoarthritis based on a study of several Japanese patient populations. The allelic odds ratio is 1.45 (CI: 1.27-1.66, p = 3.4 x 10e-8) for the minor allele, which is the (T) allele (in dbSNP orientation). [PMID 18622395]

OMIM	612401
Desc
Variant
Related	also

[PMID 20238217] Lack of evidence for association between DVWA gene polymorphisms and developmental dysplasia of the hip in Chinese Han population

[PMID 19181678] Large replication study and meta-analyses of DVWA as an osteoarthritis susceptibility locus in European and Asian populations.