SIRT1
From SNPedia
| is a | gene |
| is | mentioned by |
| Full name | sirtuin 1 |
| EntrezGene | 23411 |
| PheGenI | 23411 |
| VariationViewer | 23411 |
| ClinVar | SIRT1 |
| GeneCards | SIRT1 |
| dbSNP | 23411 |
| Diseases | SIRT1 |
| SADR | 23411 |
| HugeNav | 23411 |
| wikipedia | SIRT1 |
| SIRT1 | |
| gopubmed | SIRT1 |
| EVS | SIRT1 |
| HEFalMp | SIRT1 |
| MyGene2 | SIRT1 |
| 23andMe | SIRT1 |
| UniProt | Q96EB6 |
| Ensembl | ENSG00000096717 |
| OMIM | 604479 |
| # SNPs | 23 |
| Max Magnitude | Chromosome position | Summary | |
|---|---|---|---|
| rs10997870 | 0 | 67,908,257 | |
| rs10997875 | 0 | 67,920,067 | |
| rs11599176 | 0 | 67,894,017 | |
| rs12413112 | 0 | 67,892,108 | |
| rs12778366 | 0 | 67,883,321 | |
| rs144124002 | 0 | 67,887,495 | |
| rs1467568 | 0 | 67,915,401 | |
| rs2236318 | 0 | 67,888,811 | |
| rs2236319 | 0 | 67,889,462 | |
| rs2273773 | 0 | 67,906,841 | |
| rs2394443 | 0 | 67,884,583 | |
| rs33957861 | 0 | 67,887,218 | |
| rs34701705 | 0 | 67,908,026 | |
| rs35689145 | 0 | 67,900,009 | |
| rs35706870 | 0 | 67,883,859 | |
| rs36107781 | 0 | 67,891,561 | |
| rs3740051 | 0 | 67,884,201 | |
| rs3758391 | 2.4 | 67,883,584 | |
| rs4746720 | 0 | 67,917,073 | |
| rs7069102 | 0 | 67,903,362 | |
| rs773025707 | 0 | 67,908,022 | |
| rs7896005 | 0 | 67,891,367 | |
| rs932658 | 0 | 67,884,459 |
news SIRT1 seems to prevent a decline in levels of BDNF. People with Huntington disease tend to have low levels of BDNF.
http://www.cell.com/cell-metabolism/abstract/S1550-4131(13)00049-1 Identification of a SIRT1 Mutation in a Family with Type 1 Diabetes
