Talk:Educational attainment
The time has perhaps arrived for snpedia to create PGS genosets. The latest EA GWAS research with 1.1 million sample size has now achieved a socially relevant level of precision. The effect sizes of the 1271 SNPs could be used to create such a PGS. Might also be helpful to have a PGS for each chromosome and allow users to simulate PGS for offspring. --J1 (talk) 15:44, 25 July 2018 (UTC)
These 1271 significant SNPs are from the supplementary tables of https://www.nature.com/articles/s41588-018-0147-3#Sec34 . --J1 (talk) 16:15, 25 July 2018 (UTC)
SNP Chr Position Allele 1 Allele2 Frequency Allele 1 Effect size rs9859556 3 49455986 T G 0.3132 0.0290 rs7029718 9 23358495 A G 0.4108 0.0244 rs1334297 13 58335375 A G 0.7375 0.0257 rs9375188 6 98555272 T C 0.4847 0.0212 rs2526398 3 50187596 C G 0.3468 -0.0222 rs13018640 2 100821545 T C 0.6017 -0.0215 rs34305371 1 72733610 A G 0.0985 0.0314 rs6449503 5 60095272 A G 0.5038 0.0185 rs1689510 12 56396768 C G 0.3315 0.0194 rs11082011 18 35145122 T C 0.6716 0.0194 rs1008078 1 91189731 T C 0.4019 -0.0182 rs61104616 5 88163771 A G 0.5249 -0.0172 rs12076635 1 44026656 C G 0.7811 0.0207 rs66568921 3 85672018 T G 0.6441 -0.0181 rs56319902 17 43871982 T C 0.2155 -0.0206 rs73344830 10 103816828 A G 0.4181 0.0170 rs11678980 2 162101261 A G 0.4527 -0.0166 rs11588857 1 204587047 A G 0.2131 0.0199 rs10773002 12 123746961 A T 0.2520 0.0185 rs176218 14 29600506 T G 0.1958 0.0200 rs7849487 9 1757274 T G 0.6578 -0.0167 rs10189857 2 60713235 A G 0.5654 0.0158 rs4787457 16 28555400 A G 0.6339 0.0162 rs4919624 10 104021085 A G 0.8022 0.0193 rs111226181 3 49931760 T G 0.1773 -0.0201 rs35417702 7 71739916 T C 0.5235 -0.0152 rs55736314 3 71586293 C G 0.5990 -0.0154 rs6452793 5 87818174 T G 0.2340 0.0175 rs10215082 7 92657985 A G 0.4661 -0.0149 rs1320139 2 144158177 C G 0.4270 -0.0149 rs62262671 3 49649873 A G 0.8634 0.0213 rs3897821 1 243420388 A G 0.6654 0.0154 rs6557171 6 152234593 T C 0.3232 -0.0155 rs13240401 7 2194396 T C 0.7812 0.0176 rs2568955 1 72762169 T C 0.2481 -0.0165 rs324885 5 87897271 A C 0.5257 0.0142 rs363096 4 3180021 T C 0.4245 -0.0143 rs10931821 2 199495830 A T 0.4852 -0.0141 rs76076331 2 10977585 T C 0.1346 0.0206 rs2992037 1 43949810 A G 0.3223 0.0149 rs17411339 18 50807359 A G 0.5612 0.0140 rs7683416 4 106152984 T C 0.4592 0.0139 rs12028010 1 41764471 T C 0.7711 0.0164 rs113520408 7 128402782 A G 0.2756 0.0155 rs12375949 9 124617900 T C 0.4312 -0.0138 rs71413877 2 100924822 A G 0.0410 0.0351 rs11157931 14 23403193 A C 0.3924 -0.0139 rs9490512 6 98537993 A G 0.4496 -0.0136 rs9411331 9 134883419 A C 0.6840 0.0145 rs72819118 2 100451357 T C 0.0942 -0.0231 rs660001 5 113866598 A G 0.2113 -0.0164 rs7924036 10 65191645 T G 0.5124 0.0133 rs12468040 2 44854981 T G 0.3819 0.0137 rs13010288 2 51824512 T G 0.1288 0.0198 rs4500960 2 162818621 T C 0.4647 -0.0131 rs1054442 12 49389320 A C 0.6223 -0.0136 rs746839 8 142617261 C G 0.6283 0.0135 rs11772232 7 1856273 T C 0.1691 0.0177 rs4490539 5 60685757 A G 0.6983 0.0142 rs10810099 9 14161927 A G 0.2734 -0.0146 rs9616947 22 51151631 T C 0.3818 -0.0134 rs7590368 2 10961474 T C 0.7335 -0.0146 rs12506221 4 67899235 T G 0.4360 -0.0130 rs10875121 1 98417446 C G 0.8361 0.0174 rs12761761 10 133775375 T C 0.2395 0.0153 rs2725370 8 30852826 T C 0.3017 -0.0141 rs56391344 15 78006899 A G 0.2526 0.0148 rs72962169 11 72365669 T C 0.1595 -0.0174 rs11675476 2 193853269 T C 0.5224 -0.0127 rs2838006 21 42653567 T C 0.3597 0.0132 rs72828517 6 19036035 T C 0.8273 -0.0168 rs11774212 8 145686505 T C 0.5163 0.0128 rs72829857 6 16966052 A G 0.7610 -0.0149 rs17568389 7 8091876 A T 0.5087 0.0127 rs2179152 6 26325888 T C 0.3673 -0.0131 rs79265434 7 24621381 A G 0.8834 -0.0197 rs62182994 2 212599303 T C 0.6894 0.0137 rs7323027 13 58693790 A G 0.3719 0.0130 rs2290601 3 108112760 T C 0.7720 -0.0149 rs178183 14 26979412 T C 0.2455 0.0145 rs171697 5 103956516 C G 0.6712 0.0133 rs112375785 6 98224217 A G 0.1435 0.0184 rs6065080 20 59832791 T C 0.3589 -0.0130 rs2545795 5 176887106 A C 0.4437 0.0125 rs4757957 11 12881398 C G 0.6911 0.0133 rs613872 18 53210302 T G 0.8285 -0.0163 rs13107325 4 103188709 T C 0.0721 -0.0239 rs728054 7 137072364 A G 0.3561 -0.0128 rs57352738 7 133304694 A T 0.2040 -0.0152 rs10460095 18 22624708 A G 0.5714 -0.0124 rs790647 10 106776484 A C 0.2278 -0.0145 rs9349956 6 14718260 A C 0.8211 -0.0159 rs6715849 2 100306378 A G 0.4401 -0.0122 rs575113 1 110046373 A G 0.2941 0.0133 rs76577427 1 110761099 C G 0.9006 0.0203 rs9616906 22 51104680 A G 0.4477 0.0122 rs4719944 7 3496032 T C 0.5462 -0.0121 rs9289300 3 127144988 T C 0.8412 -0.0164 rs7920624 10 67963186 A T 0.4783 0.0120 rs72671456 14 29662737 A G 0.1374 -0.0174 rs12643771 4 140753103 T C 0.3094 0.0130 rs4726070 7 151328218 A G 0.6021 0.0122 rs362307 4 3241845 T C 0.0772 -0.0226 rs11210400 1 74490459 A C 0.5380 0.0120 rs17563464 5 26913774 A C 0.2173 -0.0147 rs717996 12 84133820 T C 0.5986 -0.0122 rs7526112 1 93747683 T G 0.6406 0.0124 rs17502934 2 50994255 T G 0.1489 -0.0167 rs9882532 3 16865845 T C 0.6368 0.0124 rs6493265 15 47513253 T C 0.3915 -0.0122 rs17489649 5 109156184 A G 0.6788 0.0127 rs76878669 11 66092567 C G 0.7609 0.0141 rs10496091 2 61482261 A G 0.2841 -0.0131 rs4467547 4 21945933 T G 0.4070 0.0121 rs3026996 1 159167290 A C 0.7606 0.0138 rs72624911 3 49064576 T C 0.0475 0.0282 rs9933256 16 1246748 A G 0.5558 0.0119 rs2923424 8 42382222 A G 0.6069 0.0120 rs635754 1 96484940 A G 0.5809 0.0119 rs17428076 2 172851936 C G 0.7598 0.0137 rs7977614 12 110115286 A G 0.7143 -0.0134 rs77609760 2 142358950 A G 0.9346 0.0236 rs12591647 15 65959729 T C 0.8171 -0.0152 rs6824567 4 2883172 T C 0.2827 0.0130 rs12957463 18 37412228 A G 0.7953 0.0146 rs2496482 14 99750164 T C 0.4161 0.0121 rs11663602 18 77578191 A C 0.2761 -0.0130 rs75177132 19 4386911 T C 0.0476 0.0298 rs10899282 11 76504698 A G 0.2279 0.0140 rs2081652 4 159862913 A T 0.6610 0.0123 rs7974852 12 14511679 A C 0.5235 0.0117 rs13318986 3 82533639 A G 0.3311 0.0124 rs2570497 2 104441546 T C 0.6367 -0.0121 rs17598675 4 176647637 T C 0.5132 -0.0116 rs34155847 4 3252130 A G 0.2483 0.0135 rs11121177 1 8445946 A G 0.1785 0.0151 rs34106693 2 101151830 C G 0.8318 0.0159 rs4984682 16 740404 C G 0.7674 -0.0138 rs6704768 2 233592501 A G 0.5648 -0.0116 rs114468556 5 92870246 A T 0.0421 0.0293 rs1569092 1 74858724 A G 0.1520 0.0160 rs4691601 4 160599341 A T 0.4571 -0.0115 rs2910823 5 59498175 T G 0.5359 0.0115 rs10984445 9 121980586 A G 0.4604 0.0115 rs34098770 16 12237812 A G 0.1520 -0.0160 rs6569077 6 98212409 T C 0.3894 0.0118 rs4984541 15 96911139 A G 0.7666 -0.0138 rs7326331 13 91615838 A G 0.2761 -0.0128 rs62260764 3 47990500 C G 0.2559 -0.0132 rs9655780 7 104667334 A G 0.8287 -0.0153 rs737945 22 30202774 C G 0.4442 -0.0115 rs10166286 2 101128095 T C 0.1730 0.0151 rs12646523 4 170944698 T C 0.2483 -0.0132 rs13163062 5 106955451 T C 0.4260 0.0115 rs6442126 3 48525955 A T 0.6593 -0.0121 rs11081529 18 75902735 T C 0.7112 0.0126 rs73581580 9 140251458 A G 0.1248 -0.0181 rs5754753 22 34296751 T C 0.7178 -0.0126 rs1656614 15 47800513 C G 0.3140 0.0122 rs6690195 1 96221653 T C 0.4907 -0.0113 rs35319653 4 140903155 T C 0.3433 0.0119 rs62247449 3 64430551 C G 0.4357 0.0114 rs6918506 6 26577857 C G 0.5379 0.0113 rs115000530 3 69930625 A T 0.9451 -0.0250 rs10979613 9 111687584 T C 0.6389 -0.0117 rs17248751 16 61579618 A G 0.7827 -0.0136 rs2998299 14 84997363 T G 0.2137 -0.0136 rs10041403 5 67805272 T C 0.8339 0.0151 rs11115056 12 82258775 A G 0.0995 0.0187 rs62379838 5 120102028 T C 0.6953 0.0121 rs73961845 2 144478983 A G 0.6170 -0.0114 rs11736863 4 23729566 A G 0.1895 0.0142 rs3812281 7 135082751 T C 0.6016 0.0113 rs9556958 13 99100046 T C 0.5233 -0.0110 rs6932108 6 98713992 C G 0.0798 -0.0210 rs11732657 4 172427073 A G 0.7504 -0.0126 rs13422673 2 155474355 T C 0.4659 -0.0110 rs2052285 16 51188432 A G 0.5959 0.0112 rs27220 5 59775136 A G 0.3562 -0.0114 rs488476 11 95543715 C G 0.6191 -0.0113 rs978807 18 36898459 A G 0.1885 0.0139 rs28512462 16 24711806 C G 0.3789 0.0112 rs3895736 3 48658467 A C 0.1728 0.0144 rs2764684 1 58537919 T C 0.8266 0.0143 rs10892807 11 121998254 T C 0.5671 0.0109 rs17669337 5 92187932 T C 0.4133 -0.0110 rs12342546 9 126329270 A G 0.2441 -0.0128 rs61527214 16 83608599 A G 0.4113 0.0110 rs8024 1 201845575 A C 0.3294 -0.0115 rs7603132 2 4951548 A G 0.1938 0.0137 rs10940921 5 30808645 T G 0.4194 0.0111 rs6731373 2 68503044 A G 0.3390 -0.0115 rs350281 16 12231739 T G 0.6825 -0.0117 rs303752 18 21074255 A G 0.4067 -0.0110 rs767943 6 23446691 A C 0.2690 -0.0122 rs9375403 6 98831636 C G 0.2423 0.0126 rs7254263 19 30741257 T C 0.2850 -0.0119 rs11716398 3 50699715 A G 0.8663 0.0159 rs803619 1 44465419 T C 0.1076 -0.0173 rs4320563 8 87769961 A G 0.5093 0.0109 rs11871429 17 42920929 A G 0.7727 0.0128 rs10761251 9 96421546 A T 0.6633 0.0113 rs6493275 15 47676579 A T 0.7885 0.0131 rs1866823 8 57436577 A G 0.5444 0.0107 rs7575637 2 145796251 A G 0.4538 0.0107 rs9529146 13 31785404 T C 0.2282 0.0127 rs35016816 16 10266115 T C 0.8990 0.0176 rs4848924 2 124991887 A C 0.7100 -0.0117 rs2406253 7 100077273 A G 0.8053 0.0135 rs9267677 6 31892641 T C 0.9029 0.0180 rs1747714 10 11161316 T C 0.5287 0.0106 rs929511 7 8003017 T C 0.1254 -0.0160 rs7108020 11 131289820 A C 0.6475 0.0111 rs1729412 2 201083598 T C 0.4224 -0.0107 rs10057590 5 124335247 A C 0.4724 0.0106 rs77702819 2 101328728 T G 0.0907 0.0187 rs6450476 5 57771087 A G 0.2929 -0.0116 rs12602286 17 19236954 T G 0.8731 0.0160 rs13163845 5 3264389 T C 0.8488 -0.0149 rs12273435 11 133825855 A G 0.2070 -0.0132 rs77999825 7 127572977 A G 0.0343 0.0294 rs10798888 1 32199099 T G 0.1725 -0.0140 rs7931563 11 61446425 T G 0.6214 -0.0109 rs1128956 4 183724005 T G 0.8251 -0.0140 rs17565975 11 111586950 A G 0.5563 -0.0106 rs12332731 5 93033082 A T 0.1882 0.0135 rs12712269 2 107564115 T C 0.3962 -0.0107 rs12170452 22 40019773 A G 0.4507 0.0105 rs58921703 7 2322943 T C 0.3698 0.0109 rs1405876 7 86237581 T G 0.6403 0.0109 rs10515007 17 50395539 T C 0.1610 0.0143 rs35493937 2 65571139 C G 0.2305 0.0124 rs11599236 10 106454672 T C 0.5838 -0.0106 rs7972246 12 27209328 T C 0.3451 0.0110 rs7640424 3 107820063 T C 0.3063 0.0113 rs11620355 13 92044587 A G 0.0912 0.0182 rs4396896 3 86261800 A T 0.3916 -0.0107 rs401526 8 130929166 T C 0.5258 -0.0104 rs12478156 2 164379658 T C 0.6378 0.0108 rs2287838 19 9959014 A G 0.5504 -0.0104 rs6697584 1 181509718 T C 0.7852 -0.0126 rs12571549 10 111770013 A G 0.1368 0.0151 rs141729694 5 87999371 T C 0.0768 0.0195 rs1464297 2 140653749 T C 0.6490 -0.0109 rs118134876 7 11500372 T C 0.0578 -0.0223 rs17551064 7 49869771 A G 0.8378 0.0141 rs1490612 4 106410855 T G 0.0780 0.0193 rs9853928 3 103295384 T C 0.2102 -0.0127 rs4500930 2 228985505 T C 0.3449 -0.0109 rs4352658 6 88279872 T C 0.0810 -0.0190 rs12875339 13 55722033 A C 0.6449 -0.0108 rs10060023 5 124304677 T C 0.3276 0.0110 rs34720381 1 171455322 T C 0.0907 -0.0180 rs7460106 8 143534777 T C 0.7620 -0.0123 rs10805383 5 63034606 A G 0.4879 -0.0103 rs61997667 14 57280046 T C 0.1511 -0.0144 rs55986781 2 60655551 T C 0.0823 0.0187 rs11657342 17 79355294 A G 0.3670 0.0140 rs13085461 3 24950387 C G 0.4740 0.0103 rs2256965 6 31555130 A G 0.4188 0.0106 rs11542663 6 119215402 A C 0.6947 0.0112 rs144336753 8 143356114 A G 0.0181 0.0388 rs12145078 1 197822977 A T 0.2074 -0.0127 rs4426420 18 35104386 T C 0.1600 -0.0140 rs17048801 4 137529847 A T 0.3909 -0.0106 rs1120924 4 5228939 T C 0.3362 0.0108 rs2478208 13 81471113 C G 0.5204 -0.0103 rs2364544 1 41833162 A G 0.3912 -0.0105 rs1167827 7 75163169 A G 0.4347 0.0104 rs28735993 22 51135595 A T 0.8844 0.0162 rs56099375 8 77372988 T C 0.2410 0.0120 rs17048855 3 8258174 A G 0.3426 0.0108 rs479018 11 66060546 A G 0.3255 0.0109 rs585557 11 65663547 A G 0.8014 0.0128 rs10951590 7 39091043 T C 0.3275 -0.0109 rs77702622 8 143367857 A G 0.0614 -0.0213 rs72771860 5 87974682 T G 0.0686 -0.0211 rs34748029 2 104060003 A C 0.0876 0.0185 rs61755388 7 126541317 T C 0.7878 0.0125 rs12503522 4 94543233 T C 0.2820 -0.0113 rs9886703 9 82246351 A T 0.1671 -0.0136 rs72482130 2 237054356 T C 0.8464 0.0141 rs77025239 3 180734185 A G 0.1559 -0.0140 rs2014830 3 50172397 T C 0.3139 0.0110 rs111852224 18 25596884 T C 0.1227 0.0156 rs4384309 10 133110596 A G 0.4641 0.0102 rs7560871 2 145616899 A G 0.0739 -0.0193 rs12524795 6 3464074 T C 0.4374 0.0102 rs72622559 3 175672897 T C 0.2301 -0.0120 rs9386110 6 145626208 T C 0.8917 -0.0163 rs62179650 2 189135884 A G 0.2995 0.0112 rs6065784 20 43717435 C G 0.6953 0.0110 rs4673840 2 215363241 T C 0.8420 -0.0138 rs56085180 7 2143594 A G 0.0366 -0.0269 rs2043187 18 50394405 A G 0.3840 0.0107 rs1329044 9 23747791 T C 0.8276 0.0134 rs12750688 1 98757620 C G 0.7406 0.0116 rs3809634 16 53538157 A G 0.6842 -0.0109 rs62177359 2 161290337 A C 0.9653 -0.0275 rs75203411 2 100513153 T C 0.1713 0.0135 rs4877516 9 82442731 A T 0.4417 -0.0101 rs4899012 14 61003889 C G 0.6019 -0.0103 rs11100237 4 160477041 A G 0.5242 -0.0101 rs3768480 1 110530995 C G 0.4523 0.0101 rs4358358 4 30970822 A G 0.6937 0.0109 rs12774577 10 104959487 T C 0.8545 0.0142 rs74545339 8 135440608 A G 0.1142 -0.0158 rs7430651 3 116582186 T C 0.2863 -0.0111 rs730384 14 74889870 A G 0.4388 0.0101 rs34067381 3 123594419 T G 0.3617 -0.0104 rs969512 4 147872742 A T 0.6596 -0.0106 rs4497562 13 62612604 A G 0.7295 0.0112 rs6994287 8 9340932 A G 0.4055 0.0102 rs6760887 2 161859760 T C 0.2447 0.0155 rs9888796 16 68297589 T C 0.2625 0.0113 rs11021432 11 95837674 A T 0.3692 0.0103 rs11703948 22 38817047 A G 0.9026 -0.0168 rs12682775 9 135490491 T C 0.7754 -0.0119 rs165633 22 29880773 A G 0.7575 -0.0116 rs10752262 10 12395100 T C 0.4192 0.0102 rs981230 5 59039858 T C 0.4793 0.0100 rs77201694 1 44347087 A G 0.1213 0.0156 rs56405138 4 166126745 A T 0.1231 0.0153 rs72636697 4 68016609 T C 0.1551 -0.0140 rs62340636 4 176940335 T G 0.6254 0.0103 rs995698 9 87997869 A G 0.5380 -0.0099 rs62155873 2 105969362 T C 0.1221 -0.0151 rs114593137 1 241876565 A T 0.7930 -0.0122 rs35929923 7 21400525 A G 0.2495 -0.0114 rs891793 15 27256021 C G 0.5403 -0.0099 rs10204051 2 103775435 T G 0.4055 -0.0101 rs73648455 9 14077378 T C 0.0797 -0.0183 rs192436652 19 54960747 T C 0.0268 -0.0319 rs175325 20 22317310 A T 0.5966 -0.0100 rs60096640 6 27636313 A G 0.8926 0.0159 rs12405889 1 235597252 T G 0.4890 -0.0098 rs9929556 16 62193640 T G 0.5688 -0.0099 rs17604349 16 72210865 A G 0.1852 0.0127 rs2216144 12 97666478 T C 0.5306 0.0098 rs56174996 1 91145181 A G 0.1359 -0.0143 rs13197257 6 128333682 T G 0.2790 0.0109 rs6969783 7 117593308 A T 0.4705 -0.0098 rs4846724 1 221967817 A G 0.5347 0.0098 rs356999 2 60811584 A G 0.3802 -0.0101 rs72677177 1 72120034 A G 0.4017 0.0100 rs6573559 14 64923166 T G 0.3152 0.0105 rs12638072 3 65654480 A G 0.2992 -0.0107 rs9929993 16 7664875 T C 0.3610 -0.0102 rs1245829 12 79648170 A T 0.5814 -0.0099 rs79798166 5 59152140 A G 0.0884 0.0172 rs3735478 7 44800176 T G 0.2932 0.0108 rs77719387 3 49917021 A T 0.0174 -0.0403 rs118093058 11 62413673 T G 0.1330 0.0146 rs59480703 8 9653130 C G 0.1936 -0.0123 rs4881269 10 4031519 A G 0.3818 0.0100 rs8008382 14 104054425 T C 0.3009 -0.0106 rs7617204 3 160821969 A G 0.5223 -0.0097 rs1117152 12 15438032 T G 0.7010 0.0106 rs7041702 9 33053430 A G 0.7406 -0.0111 rs1434630 5 136557055 T G 0.1479 -0.0137 rs4839155 1 112161489 T G 0.7671 0.0115 rs11687736 2 225405122 A T 0.6764 -0.0105 rs10145520 14 21930932 T G 0.8031 -0.0122 rs12613500 2 180928465 C G 0.4238 0.0098 rs711793 2 174175921 T C 0.3474 0.0103 rs7910403 10 87039251 T G 0.1952 0.0122 rs12285074 11 116762028 A G 0.1012 0.0161 rs9267658 6 31845985 T C 0.1428 0.0138 rs7040995 9 92226172 C G 0.5324 0.0097 rs35811586 2 233743794 T C 0.0547 0.0217 rs9373363 6 143150043 A G 0.7485 -0.0111 rs79994730 1 75562222 T C 0.0426 0.0240 rs721579 17 43370481 T C 0.2617 -0.0110 rs12764593 10 107491895 C G 0.0622 0.0202 rs62420387 6 98404243 T C 0.0750 -0.0184 rs74415461 16 89990843 T C 0.0843 0.0176 rs74747621 2 229061868 T C 0.1124 0.0153 rs7147473 14 30608538 A G 0.6719 -0.0103 rs74091672 1 73978572 A C 0.8881 -0.0153 rs77554090 3 65711935 T C 0.0731 -0.0186 rs981883 5 57107989 A G 0.3886 0.0099 rs35104491 6 97390463 A G 0.1849 0.0124 rs10937240 3 185802823 T C 0.1899 -0.0123 rs56171318 18 35272539 T C 0.1431 -0.0137 rs1637770 7 2190385 T C 0.0683 0.0191 rs13133213 4 15646794 A G 0.4980 0.0096 rs6715321 2 100109001 T C 0.4277 -0.0097 rs7317761 13 100753796 C G 0.7355 0.0109 rs10773208 12 122970156 T C 0.2526 -0.0110 rs4741571 9 1667814 A G 0.6723 -0.0102 rs6917204 6 145284716 T C 0.7951 0.0119 rs6743032 2 126024787 A G 0.0926 -0.0165 rs17190418 13 58746132 T C 0.0537 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