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Tooth Development

From SNPedia


Permanent tooth development[edit]

SNPs and genes[edit]

Some SNPs based on GWAS studiesː


SNPs in these genes are associated with permanent tooth development, according to GWAS studiesː

Publications[edit]

[PMID 21931568OA-icon.png] Genome-wide association study identifies four loci associated with eruption of permanent teeth.

Primary tooth development (number of teeth)[edit]

SNPs and genes[edit]

Some SNPs associated with primary tooth development (number of teeth), based on GWAS studiesː


SNPs in these genes are associated with number of teeth development, according to GWAS studiesː

Publications[edit]

[PMID 23704328OA-icon.png] Genome-wide association study of primary tooth eruption identifies pleiotropic loci associated with height and craniofacial distances.

Primary tooth development (time to first tooth eruption)[edit]

SNPs and genes[edit]

Some SNPs associated with time to first tooth eruption, based on GWAS studiesː


SNPs in these genes are associated with time to first tooth eruption, according to GWAS studiesː


Publications[edit]

[PMID 23704328OA-icon.png] Genome-wide association study of primary tooth eruption identifies pleiotropic loci associated with height and craniofacial distances.

Shovel-shaped incisors[edit]

SNPs and genes[edit]

SNPs


Genes

Publications[edit]

[PMID 22648185] Effects of an Asian-specific nonsynonymous EDAR variant on multiple dental traits.

[PMID 19804850OA-icon.png] A common variation in EDAR is a genetic determinant of shovel-shaped incisors.

Tooth agenesis[edit]

Tooth agenesis (third molar) is counted as separate reported traits in GWAS studiesː

SNPs and genes[edit]

  • rs1469622 Tooth agenesis, third molar
  • rs938036 Tooth agenesis, mandibular third molar
  • rs906628 Tooth agenesis, mandibular third molar


SNPs in these genes are associated with tooth agenesis, according to GWAS studiesː

Publications[edit]

[PMID 27365112] Mutations in MSX1, PAX9 and MMP20 genes in Saudi Arabian patients with tooth agenesis.

[PMID 24172245] A genome-wide association study of third molar agenesis in Japanese and Korean populations.