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ADRB1

From SNPedia

is agene
is mentioned by
Full nameadrenergic, beta-1-, receptor
EntrezGene153
PheGenI153
VariationViewer153
ClinVarADRB1
GeneCardsADRB1
dbSNP153
SADR153
HugeNav153
wikipediaADRB1
googleADRB1
gopubmedADRB1
EVSADRB1
HEFalMpADRB1
MyGene2ADRB1
23andMeADRB1
UniProtP08588
EnsemblENSG00000043591
OMIM109630
# SNPs2
 Max MagnitudeChromosome positionSummary
rs18012523114,044,277
rs18012531.1114,045,297

Polymorphisms in the beta-1 adrenergic receptor gene ADRB1 may explain up to 20% of the variability in how individuals respond to treatment with beta blocker drugs used to help lower blood pressure. It may also affect lipid metabolism.

Associated SNPs in the gene include:

rs1801253 may be a susceptibility polymorphism for lipid metabolism disruption. [PMID 24972470]

Dionne et al. (2002) found that the arg389 allele was associated with greater body weight with each arg389 allele being associated with a 2.91 kg greater weight.