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MC4R

From SNPedia

is agene
is mentioned by
Full namemelanocortin 4 receptor
EntrezGene4160
PheGenI4160
VariationViewer4160
ClinVarMC4R
GeneCardsMC4R
dbSNP4160
SADR4160
HugeNav4160
wikipediaMC4R
googleMC4R
gopubmedMC4R
EVSMC4R
HEFalMpMC4R
MyGene2MC4R
23andMeMC4R
UniProtP32245
EnsemblENSG00000166603
OMIM155541
# SNPs26
 Max MagnitudeChromosome positionSummary
rs108717772.160,184,530
rs1187299260,373,354
rs121913557060,372,202
rs121913558060,372,178
rs121913559060,372,045
rs121913560060,371,842
rs121913561060,371,529
rs121913562060,371,538
rs121913563060,371,827
rs121913564060,371,403
rs121913565060,372,061
rs121913566060,372,165
rs121913567060,371,694
rs121917829060,371,489
rs12970134060,217,517
rs13447324060,372,245
rs13447325060,372,240
rs13447331060,371,970
rs177823132.560,183,864
rs193922685060,371,812
rs193922687060,371,513
rs22296162.160,372,043
rs52804924060,371,454
rs751160202060,372,144
rs79783591060,371,544
rs808752260,373,245

Melanocortin 4 receptor is a protein that in humans is encoded by the MC4R gene. It encodes the MC4 protein, a G protein-coupled receptor that binds α-melanocyte stimulating hormone (α-MSH). In murine models MC4 receptors have been found to be involved in feeding behaviour, the regulation of metabolism, sexual behaviour, and male erectile function.Wikipedia

[PMID 27701398] Divergent effects of central melanocortin signalling on fat and sucrose preference in humans

Fat preference G252S 2
Fat preference Y80X 1
Fat preference R236C 1
Fat preference I125K 4
Fat preference C271Y 3 rs121913562
Fat preference Y35X; D37V 2 rs13447324; rs13447325
Fat preference I137T 1
Sucrose preference I125K 2
Sucrose preference E61K 2
Sucrose preference C271Y 2 rs121913562
Sucrose preference A144S 1
Sucrose preference Y35X; D37V 2 rs13447324; rs13447325
Sucrose preference F280AfsX12 1 rs193922687