TP53

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 GeneRIF     7157
 dbSNP        7157
 PubMed     7157
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 HEFalMp     TP53
Chromosome position Summary
Rs1042522 75201967,520,196
Rs11540652 75182627,518,262
Rs12951053 75181317,518,131
Rs17887200 75117957,511,795
Rs28934271 75175967,517,596
Rs28934571 75182587,518,258
Rs28934572 75182747,518,274
Rs28934573 75182837,518,283
Rs28934574 75178187,517,818
Rs28934575 75182727,518,272
Rs28934576 75178447,517,844
Rs28934577 75182357,518,235
Rs28934578 75191307,519,130
Rs28934873 75192567,519,256
Rs28934874 75192037,519,203
Rs28934875 75192427,519,242


Variations in this gene influence Li-Fraumeni syndrome, and have also been linked to cancers.

TP53 SNPs associated with increased risk for breast cancer include:

  • rs1042522, also known as P72R, Arg72, or Arg72Pro. The risk allele is C.
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