The research article under this SNP, Genome-wide association and linkage study in the Amish detects a novel candidate late-onset Alzheimer disease gene. Cummings, et al. 2012, does not mention rs6468852 in the abstract or in the article, http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419486/. The abstract for a presentation, Genome-wide association study in the Amish indicates non-APOE genetic effects for dementia. A. Davis, et al. 2009, http://www.ashg.org/2009meeting/abstracts/fulltext/f10932.htm, lists rs6468852, however a thorough search failed to yield any published research linking rs6468852 with LOAD. My suggestion is to remove association of this SNP with LOAD until research linking rs6468852 with LOAD is published.