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UGT2B17

From SNPedia

is agene
is mentioned by
EntrezGene7367
PheGenI7367
VariationViewer7367
ClinVarUGT2B17
GeneCardsUGT2B17
dbSNP7367
SADR7367
HugeNav7367
wikipediaUGT2B17
googleUGT2B17
gopubmedUGT2B17
EVSUGT2B17
HEFalMpUGT2B17
MyGene2UGT2B17
23andMeUGT2B17
# SNPs8
 Max MagnitudeChromosome positionSummary
rs1002577168,539,507
rs11723091068,539,752
rs11938019068,559,644
rs13327941068,556,427
rs655218268,567,230
rs6857249068,569,184
rs743582768,549,226
rs7436338068,567,561


[PMID 19789632] This gene harbors Copy Number Variations which vary significantly among populations.

[PMID 18334593] Deletion of both copies of this gene alters testosterone metabolism making steroid use undetectable.

One type of deletion polymorphism in the UGT2B17 gene lowered urinary testosterone glucuronide levels and that polymorphism allele was found at a "frequency of 29% in Swedes and 78% in Koreans."

thesis abstract


It may be possible to detect the deletion by checking the snps below which occur on the Illumina 1M chip.

the 23andMe chip does not test for this.

UGT2B17 has been associated with Prostate cancer [1]