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User:JohnLloydScharf/Type II Diabetes

From SNPedia

Type II Diabetes[edit]


  • "rs1007888","22","22571101","TC"
rs1007888(C;C) was associated with an increased risk of type-2 diabetes in women [hazard ratio (95% CI) 1.74 (1.02-2.97)], but not in men [1.17 (0.75-1.81)]. [PMID 17712545]


  • "rs1801239","10","16959058","TT"=CC Orientation minus
In particular, among individuals with diabetes, each copy of the C allele at rs1801239 was associated with an odds ratio of 1.27 for microalbuminuria (95% CI: 1.11 to 1.45)
http://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?rs=1801239
http://www.snpedia.com/index.php/Rs1801239


  • "rs5945326","X","152553116","GG"
[PMID 21643948] Replication study of novel risk variants in six genes with type 2 diabetes and related quantitative traits in the Han Chinese lean individuals http://www.snpedia.com/index.php/Rs5945326


  • "rs1048118","X","47368744","GG"
[PMID 20122735] Screening of DNA-variants in the properdin gene (CFP) in age-related macular degeneration (AMD)


  • "rs10434","6","43861190","AG"
[PMID 19553626] Common sequence variation in the VEGFA gene predicts risk of diabetic retinopathy


  • rs12255372 10 114798892 GG
Genotype Effect
rs12255372(G;G)
rs12255372(G;T) 1.3x increased type-2 diabetes risk