rs1230025
From SNPedia
| Orientation | minus |
| Stabilized | minus |
| Make rs1230025(A;A) |
| Make rs1230025(A;T) |
| Make rs1230025(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 4 |
| Position | 99265219 |
| Gene | LOC100507053 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs1230025 |
| dbSNP (classic) | rs1230025 |
| ClinGen | rs1230025 |
| ebi | rs1230025 |
| HLI | rs1230025 |
| Exac | rs1230025 |
| Gnomad | rs1230025 |
| Varsome | rs1230025 |
| LitVar | rs1230025 |
| Map | rs1230025 |
| PheGenI | rs1230025 |
| Biobank | rs1230025 |
| 1000 genomes | rs1230025 |
| hgdp | rs1230025 |
| ensembl | rs1230025 |
| geneview | rs1230025 |
| scholar | rs1230025 |
| rs1230025 | |
| pharmgkb | rs1230025 |
| gwascentral | rs1230025 |
| openSNP | rs1230025 |
| 23andMe | rs1230025 |
| SNPshot | rs1230025 |
| SNPdbe | rs1230025 |
| MSV3d | rs1230025 |
| GWAS Ctlg | rs1230025 |
| GMAF | 0.135 |
| Max Magnitude | 0 |
| ? | (A;A) (A;T) (T;T) | 28 |
|---|---|---|
|
| ||
source rs1230025 and more than 3 beers per day linked to a 75% increased risk of developing gastric cancer. Wine were liquor not associated.
[PMID 22144473] Genetic variation in alcohol dehydrogenase (ADH1A, ADH1B, ADH1C, ADH7) and aldehyde dehydrogenase (ALDH2), alcohol consumption, and gastric cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort
[PMID 17273965
] Evidence of positive selection on a class I ADH locus.
[PMID 18996923] Associations of ADH and ALDH2 gene variation with self report alcohol reactions, consumption and dependence: an integrated analysis.
[PMID 19193628] ADH single nucleotide polymorphism associations with alcohol metabolism in vivo.
