rs2334499
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Make rs2334499(C;C) |
| Make rs2334499(C;T) |
| Make rs2334499(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 11 |
| Position | 1675619 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs2334499 |
| dbSNP (classic) | rs2334499 |
| ClinGen | rs2334499 |
| ebi | rs2334499 |
| HLI | rs2334499 |
| Exac | rs2334499 |
| Gnomad | rs2334499 |
| Varsome | rs2334499 |
| LitVar | rs2334499 |
| Map | rs2334499 |
| PheGenI | rs2334499 |
| Biobank | rs2334499 |
| 1000 genomes | rs2334499 |
| hgdp | rs2334499 |
| ensembl | rs2334499 |
| geneview | rs2334499 |
| scholar | rs2334499 |
| rs2334499 | |
| pharmgkb | rs2334499 |
| gwascentral | rs2334499 |
| openSNP | rs2334499 |
| 23andMe | rs2334499 |
| SNPshot | rs2334499 |
| SNPdbe | rs2334499 |
| MSV3d | rs2334499 |
| GWAS Ctlg | rs2334499 |
| GMAF | 0.4532 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
rs2334499 is in a region of chromosome 11p15 which contains a cluster of imprinted genes.
This SNP, rs2334499, has recently been reported to have an association with type-2 diabetes. The allele that confers risk when paternally inherited is protective when maternally inherited.[PMID 20016592
]
[PMID 21278902] Genetic risk profiling for prediction of type 2 diabetes.
[PMID 23462794] Identification of CpG-SNPs associated with type 2 diabetes and differential DNA methylation in human pancreatic islets.
[PMID 23630301] Strong parent-of-origin effects in the association of KCNQ1 variants with type 2 diabetes in American Indians.
