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rs5744455

From SNPedia

Orientationminus
Stabilizedminus
Make rs5744455(C;C)
Make rs5744455(C;T)
Make rs5744455(T;T)
ReferenceGRCh38 38.1/141
Chromosome5
Position140633722
GeneCD14, TMCO6
is asnp
is mentioned by
dbSNPrs5744455
dbSNP (classic)rs5744455
ClinGenrs5744455
ebirs5744455
HLIrs5744455
Exacrs5744455
Gnomadrs5744455
Varsomers5744455
LitVarrs5744455
Maprs5744455
PheGenIrs5744455
Biobankrs5744455
1000 genomesrs5744455
hgdprs5744455
ensemblrs5744455
geneviewrs5744455
scholarrs5744455
googlers5744455
pharmgkbrs5744455
gwascentralrs5744455
openSNPrs5744455
23andMers5744455
SNPshotrs5744455
SNPdbers5744455
MSV3drs5744455
GWAS Ctlgrs5744455
GMAF0.219
Max Magnitude0

rs5744455 also known as (-651C>T) in CD14

[PMID 17438094] Haplotype analysis suggested a synergistic effect of the two SNPs (OR for the T(-651)-T(-260) haplotype, 3.39 versus OR for the C(-651)-T(-260) haplotype, 1.45; P = 0.02), which is consistent with reporter gene assays. A multiplicative joint effect between H. pylori infection and -260C>T polymorphism was observed (OR for the presence of both -260TT genotype and H. pylori infection, 4.03; 95% CI, 1.80-9.04)


[PMID 18987746OA-icon.png] Association of interacting genes in the toll-like receptor signaling pathway and the antibody response to pertussis vaccination.


[PMID 20398919] CD14 polymorphisms and serum CD14 levels through childhood: a role for gene methylation?


[PMID 24902762] Genetic variants in endotoxin signalling pathway, domestic endotoxin exposure and asthma exacerbations


[PMID 30288821] Early-life exposure to sibling modifies the relationship between CD14 polymorphisms and allergic sensitisation.