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rs666553

From SNPedia

Orientationplus
Stabilizedplus
Make rs666553(C;C)
Make rs666553(C;T)
Make rs666553(T;T)
ReferenceGRCh38 38.1/141
Chromosome11
Position101067937
GenePGR
is asnp
is mentioned by
dbSNPrs666553
dbSNP (classic)rs666553
ClinGenrs666553
ebirs666553
HLIrs666553
Exacrs666553
Gnomadrs666553
Varsomers666553
LitVarrs666553
Maprs666553
PheGenIrs666553
Biobankrs666553
1000 genomesrs666553
hgdprs666553
ensemblrs666553
geneviewrs666553
scholarrs666553
googlers666553
pharmgkbrs666553
gwascentralrs666553
openSNPrs666553
23andMers666553
SNPshotrs666553
SNPdbers666553
MSV3drs666553
GWAS Ctlgrs666553
GMAF0.1786
Max Magnitude0
? (C;C) (C;T) (T;T) 28


news The effectiveness of 17 alpha-hydroxyprogesterone caproate for prevention of recurrent preterm birth is influenced by SNPs.

Black women

  • rs471767 homozygous for the major allele treatment significantly reduced the rate of preterm birth.
  • rs578029 who had a least one copy of the major allele, treatment significantly reduced in preterm birth

non-black women

  • a least one copy of the minor allele of rs503362 had a significant reduction with treatment
  • with at least one copy of the minor allele of rs666553 had a significant reduction in very preterm birth


[PMID 21600550OA-icon.png] Progesterone receptor polymorphisms and clinical response to 17-alpha-hydroxyprogesterone caproate