[PMID 19491260] Genetic Variants on Chromosome 15q25 Associated with Lung Cancer Risk in Chinese Populations
[PMID 18519524] Variants in nicotinic receptors and risk for nicotine dependence.
[PMID 19330903] Gene by smoking interaction in hypertension: identification of a major quantitative trait locus on chromosome 15q for systolic blood pressure in Mexican-Americans.
[PMID 19443489] Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5.
[PMID 19706762] The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans.
GWAS snp
|
PMID
|
[PMID 22832964]
|
Trait
|
|
Title
|
Genome-wide meta-analyses of smoking behaviors in African Americans.
|
Risk Allele
|
C
|
P-val
|
2E-7
|
Odds Ratio
|
0.0330 None
|
[PMID 23844051] Association of CHRNA5-A3-B4 Variation with Esophageal Squamous Cell Carcinoma Risk and Smoking Behaviors in a Chinese Population
[PMID 23576140] Is susceptibility locus for lung cancer in the 15q25 nicotinic acetylcholine receptor gene cluster CHRNA5-A3-B4 associated with risk of gastric cancer?
[PMID 31942417] Chronic Obstructive Pulmonary Disease Risk and Smoking Cessation Changes Induced by CHRNA5-A3 and CHRNB3-A6 Variation in a Chinese Male Population.