rs7000448
| Orientation | plus |
| Stabilized | plus |
| Make rs7000448(C;C) |
| Make rs7000448(C;T) |
| Make rs7000448(T;T) |
| Reference | GRCh38 38.1/142 |
| Chromosome | 8 |
| Position | 127428925 |
| Gene | CASC8 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs7000448 |
| dbSNP (classic) | rs7000448 |
| ClinGen | rs7000448 |
| ebi | rs7000448 |
| HLI | rs7000448 |
| Exac | rs7000448 |
| Gnomad | rs7000448 |
| Varsome | rs7000448 |
| LitVar | rs7000448 |
| Map | rs7000448 |
| PheGenI | rs7000448 |
| Biobank | rs7000448 |
| 1000 genomes | rs7000448 |
| hgdp | rs7000448 |
| ensembl | rs7000448 |
| geneview | rs7000448 |
| scholar | rs7000448 |
| rs7000448 | |
| pharmgkb | rs7000448 |
| gwascentral | rs7000448 |
| openSNP | rs7000448 |
| 23andMe | rs7000448 |
| SNPshot | rs7000448 |
| SNPdbe | rs7000448 |
| MSV3d | rs7000448 |
| GWAS Ctlg | rs7000448 |
| GMAF | 0.416 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
rs7000448 increases susceptibility to Prostate cancer 1.19 times for carriers of the T allele [PMID 17401364
]
[PMID 20717903] Evidence for an association between prostate cancer and chromosome 8q24 and 10q11 genetic variants in African American men: The flint men's health study
[PMID 21051319] Risk of Urinary Bladder Cancer is Associated with 8q24 Variant rs9642880[T]: Results from the Los Angeles-Shanghai Case-Control Study
[PMID 22234922] 8q24 risk alleles in West African and Caribbean men
[PMID 17618282] A common genetic risk factor for colorectal and prostate cancer.
[PMID 18231127] 8q24 and prostate cancer: association with advanced disease and meta-analysis.
[PMID 18349290] Association of genetic variants at 8q24 with breast cancer risk.
[PMID 18360876] Chromosome 8q24 markers: risk of early-onset and familial prostate cancer.
[PMID 18483343] Multiple independent genetic variants in the 8q24 region are associated with prostate cancer risk.
[PMID 18577746] Multiple loci with different cancer specificities within the 8q24 gene desert.
[PMID 19155440] Meta association of colorectal cancer confirms risk alleles at 8q24 and 18q21.
[PMID 19366828] Evaluation of 8q24 and 17q risk loci and prostate cancer mortality.
[PMID 19520795] Novel single nucleotide polymorphism associations with colorectal cancer on chromosome 8q24 in African and European Americans.
[PMID 19549807] Prostate cancer risk associated loci in African Americans.
[PMID 19549893] Evaluation of the 8q24 prostate cancer risk locus and MYC expression.
[PMID 19602258] Significance of common variants on human chromosome 8q24 in relation to the risk of prostate cancer in native Japanese men.
[PMID 20039378] Estimation of genotype relative risks from pedigree data by retrospective likelihoods.
[PMID 20690139] Meta-analysis of genome-wide and replication association studies on prostate cancer.
[PMID 22382457] Racial disparities in the association between variants on 8q24 and prostate cancer: a systematic review and meta-analysis.
