Have questions? Visit https://www.reddit.com/r/SNPedia

BDNF

From SNPedia

is agene
is mentioned by
Full namebrain-derived neurotrophic factor
EntrezGene627
PheGenI627
VariationViewer627
ClinVarBDNF
dbSNP627
SADR627
HugeNav627
wikipediaBDNF
googleBDNF
gopubmedBDNF
EVSBDNF
HEFalMpBDNF
MyGene2BDNF
23andMeBDNF
UniProtP23560
EnsemblENSG00000176697
OMIM113505
# SNPs29
 Max MagnitudeChromosome positionSummary
rs1076766427,704,439
rs1083521027,674,363
rs1103009927,656,036
rs1103010027,656,039
rs1103010127,659,197
rs1103010327,660,786
rs1103010427,662,970
rs1103010727,673,288
rs1103011927,706,555
rs1227336327,723,312
rs12273539027,661,764
rs1229106327,672,554
rs13306221027,701,142
rs1691723427,676,827
rs1691723727,680,836
rs203032327,706,992
rs203032427,705,368
rs204904527,672,694
rs204904627,702,228
rs2872215127,659,629
rs41282918027,657,233
rs56164415027,700,188
rs6188880027,700,731
rs62652.627,658,369
rs710341127,678,578
rs710387327,678,770
rs8192466427,658,560
rs96236927,712,873
rs98874827,703,198

rs6265 in this gene has been linked to Alzheimer's disease.

[PMID 18518926] rs6265 aka Val66Met may influence general cognitive ability

[PMID 19018231] A study of 1749 Caucasian Americans from 250 multiplex bipolar families found evidence of association between several BDNF SNPs and risk of bipolar disorder

news SIRT1 seems to prevent a decline in levels of BDNF. People with Huntington disease tend to have low levels of BDNF.