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DPP6

From SNPedia

is agene
is mentioned by
Full namedipeptidyl-peptidase 6
EntrezGene1804
PheGenI1804
VariationViewer1804
ClinVarDPP6
GeneCardsDPP6
dbSNP1804
SADR1804
HugeNav1804
wikipediaDPP6
googleDPP6
gopubmedDPP6
EVSDPP6
HEFalMpDPP6
MyGene2DPP6
23andMeDPP6
UniProtP42658
EnsemblENSG00000130226
OMIM126141
# SNPs16
 Max MagnitudeChromosome positionSummary
rs102397940154,508,809
rs102604042154,513,713
rs12534701154,889,200
rs12666280154,717,614
rs12671878153,861,864
rs2110267153,838,604
rs2192271153,852,211
rs3807218154,669,402
rs38989153,881,331
rs6062312260154,305,155
rs64643750153,928,758
rs6947495153,855,979
rs69778200154,374,935
rs71534169154,801,156
rs758316153,934,563
rs7862051430154,794,095

Two SNPs in the DPP6 region of ch 7 have been associated with ALS:

Each shows independent increased risk for ALS, and together they form a haplotype of quite significant (statistically; 10e-9) risk though the overall odds ratio is still relatively low. [PMID 18084291] Dec07 Press Release