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FABP2

From SNPedia

is agene
is mentioned by
EntrezGene2169
PheGenI2169
VariationViewer2169
ClinVarFABP2
GeneCardsFABP2
dbSNP2169
SADR2169
HugeNav2169
wikipediaFABP2
googleFABP2
gopubmedFABP2
EVSFABP2
HEFalMpFABP2
MyGene2FABP2
23andMeFABP2
# SNPs4
 Max MagnitudeChromosome positionSummary
i6010053
rs11724758119,318,723
rs17998830119,320,747
rs5861422119,322,182


Half the U.S. population carries a gene variant which causes them to metabolize fat differently and may hurt their ability to remove sugar from the blood [1]. This difference is related to Diabetes.

[PMID 17209184] FABP2 Ala54Thr genotype is associated with glucoregulatory function and lipid oxidation after a high-fat meal in sedentary nondiabetic men and women. FABP2 Thr54 carriers have lower glucose tolerance and lower insulin action than do Ala54-homozygous persons. Furthermore, FABP Thr54 carriers have higher lipid oxidation rates, which may be the mechanism of glucoregulatory dysfunction.