Rs10735810

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Merged intors2228570
Orientationminus
Make rs10735810(C;C)
Make rs10735810(C;T)
Make rs10735810(T;T)
ReferenceGRCh38 38.1/141
Chromosome12
Position47879112
GeneVDR
is asnp
is mentioned by
dbSNPrs10735810
PheGenIrs10735810
nextbiors10735810
hapmaprs10735810
1000 genomesrs10735810
hgdprs10735810
ensemblrs10735810
gopubmedrs10735810
geneviewrs10735810
scholarrs10735810
googlers10735810
pharmgkbrs10735810
gwascentralrs10735810
openSNPrs10735810
23andMers10735810
23andMe allrs10735810
SNP Nexus

SNPshotrs10735810
SNPdbers10735810
MSV3drs10735810
StatusMerged into rs2228570
Max Magnitude
? (C;C) (C;T) (T;T) 28
[PMID 19178954] vitamin D metabolism
Rs10735810
PubMed [PMID 15459215]
Affy Probeset SNP_A-8299185
Affy Orientation reverse
On GW 5.0 0
Alleles A/B C/T
Ancestral
Population US
Allele G
Case Freq. 0.78
Control Freq. 0.62
Odds Ratio Het 3.93
Odds Ratio Hom 6.56
Odds Ratio All
Disease Osteonecrosis in acute lymphoblastic leukemia (ALL-ON)


rs10735810 increases susceptibility to Idiopathic short stature 1.33 times for heterozygotes (AG) and 1.90 times for homozygotes (GG) [PMID 10770213]

rs10735810 increases susceptibility to Osteonecrosis in acute lymphoblastic leukemia 3.93 times for heterozygotes (AG) and 6.56 times for homozygotes (GG) [PMID 15459215]

[PMID 19105801OA-icon.png] rs2228570 aka rs10735810 allele (A) observed for breast cancer odds ratio (OR) of 1.26

Neighborrs2228570
Distance1

[PMID 19383647] Past environmental sun exposure and risk of multiple sclerosis: a role for the Cdx-2 Vitamin D receptor variant in this interaction


[PMID 18587672] Vitamin D receptor variants and breast cancer risk in the Polish population

[PMID 19499989] Vitamin D receptor polymorphisms in differentiated thyroid carcinoma

[PMID 19734102] Vitamin D receptor gene polymorphisms and susceptibility to type 1 diabetes in Crete, Greece

[PMID 19758194] Association study on two vitamin D receptor gene polymorphisms and vitamin D metabolites in multiple sclerosis


[PMID 20363324] A systematic review of the association between common single nucleotide polymorphisms and 25-hydroxyvitamin D concentrations

[PMID 20473893OA-icon.png] Vitamin D receptor rs2228570 polymorphism and invasive ovarian carcinoma risk: Pooled analysis in five studies within the Ovarian Cancer Association Consortium


[PMID 21837802] Confirmation of an association between single nucleotide polymorphisms in the VDR gene with respiratory syncytial virus related disease in South African Children


[PMID 22213340] 25-hydroxyvitamin D, vitamin D receptor gene polymorphisms, and severity of Parkinson's disease


[PMID 22280097] Plasma Levels of Vitamin D in HIV Patients Initiating Antiretroviral Therapy Do Not Predict Immune Restoration Disease Associated with Mycobacterium tuberculosis.


[PMID 23173643] Vitamin D receptor gene polymorphism and cardiovascular risk variables in elderly Polish subjects


[PMID 23416105] Vitamin D status and gene transcription in immune cells


[PMID 24927719] Interrelation between genotypes of the vitamin D receptor gene and serum sex hormone concentrations in the Polish elderly population: the PolSenior study