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rs12010175

From SNPedia

Orientationplus
Stabilizedplus
Make rs12010175(A;A)
Make rs12010175(A;G)
Make rs12010175(G;G)
ReferenceGRCh38 38.1/141
ChromosomeX
Position153597180
GeneFAM58A
is asnp
is mentioned by
dbSNPrs12010175
ebirs12010175
HLIrs12010175
Exacrs12010175
Varsomers12010175
Maprs12010175
PheGenIrs12010175
hapmaprs12010175
1000 genomesrs12010175
hgdprs12010175
ensemblrs12010175
gopubmedrs12010175
geneviewrs12010175
scholarrs12010175
googlers12010175
pharmgkbrs12010175
gwascentralrs12010175
openSNPrs12010175
23andMers12010175
23andMe allrs12010175
SNP Nexus

SNPshotrs12010175
SNPdbers12010175
MSV3drs12010175
GWAS Ctlgrs12010175
GMAF0.1608
Max Magnitude
? (A;A) (A;G) (G;G) 28
GWAS snp
PMID [PMID 22961080OA-icon.png]
Trait Type 2 diabetes
Title A genome-wide association study identifies GRK5 and RASGRP1 as type 2 diabetes loci in Chinese Hans.
Risk Allele G
P-val 0.02
Odds Ratio 1.21 [1.14-1.28]

Allele G associated with 1.21x risk of Type 2 Diabetes in study of 17,492 Han Chinese and Asian control group [PMID 22961080OA-icon.png].

As (A,A) is the rare variant, it thus effectively reduces risk. In slight Linkage Disequilibrium with rs5945326 near DUSP9 gene, forming a single locus.