rs12010175
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Make rs12010175(A;A) |
| Make rs12010175(A;G) |
| Make rs12010175(G;G) |
| Reference | GRCh38 38.1/141 |
| Chromosome | X |
| Position | 153597180 |
| Gene | FAM58A |
| is a | snp |
| is | mentioned by |
| dbSNP | rs12010175 |
| dbSNP (classic) | rs12010175 |
| ClinGen | rs12010175 |
| ebi | rs12010175 |
| HLI | rs12010175 |
| Exac | rs12010175 |
| Gnomad | rs12010175 |
| Varsome | rs12010175 |
| LitVar | rs12010175 |
| Map | rs12010175 |
| PheGenI | rs12010175 |
| Biobank | rs12010175 |
| 1000 genomes | rs12010175 |
| hgdp | rs12010175 |
| ensembl | rs12010175 |
| geneview | rs12010175 |
| scholar | rs12010175 |
| rs12010175 | |
| pharmgkb | rs12010175 |
| gwascentral | rs12010175 |
| openSNP | rs12010175 |
| 23andMe | rs12010175 |
| SNPshot | rs12010175 |
| SNPdbe | rs12010175 |
| MSV3d | rs12010175 |
| GWAS Ctlg | rs12010175 |
| GMAF | 0.1608 |
| Max Magnitude | 0 |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
|
| ||
| GWAS snp | |
|---|---|
| PMID | [PMID 22961080 ]
|
| Trait | Type 2 diabetes |
| Title | A genome-wide association study identifies GRK5 and RASGRP1 as type 2 diabetes loci in Chinese Hans. |
| Risk Allele | G |
| P-val | 0.02 |
| Odds Ratio | 1.21 [1.14-1.28] |
Allele G associated with 1.21x risk of Type 2 Diabetes in study of 17,492 Han Chinese and Asian control group [PMID 22961080].
As (A,A) is the rare variant, it thus effectively reduces risk. In slight Linkage Disequilibrium with rs5945326 near DUSP9 gene, forming a single locus.
