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rs12422149

From SNPedia

Orientationplus
Stabilizedplus
Make rs12422149(A;A)
Make rs12422149(A;G)
Make rs12422149(G;G)
ReferenceGRCh38 38.1/141
Chromosome11
Position75172532
GeneSLCO2B1
is asnp
is mentioned by
dbSNPrs12422149
ebirs12422149
HLIrs12422149
Exacrs12422149
Varsomers12422149
Maprs12422149
PheGenIrs12422149
hapmaprs12422149
1000 genomesrs12422149
hgdprs12422149
ensemblrs12422149
gopubmedrs12422149
geneviewrs12422149
scholarrs12422149
googlers12422149
pharmgkbrs12422149
gwascentralrs12422149
openSNPrs12422149
23andMers12422149
23andMe allrs12422149
SNP Nexus

SNPshotrs12422149
SNPdbers12422149
MSV3drs12422149
GWAS Ctlgrs12422149
GMAF0.2016
Max Magnitude
? (A;A) (A;G) (G;G) 28
[PMID 19151602OA-icon.png] rs12422149 linked to asthma



[PMID 21266523OA-icon.png] Expression of SLCO transport genes in castration resistant prostate cancer and impact of genetic variation in SCLO1B3 and SLCO2B1 on prostate cancer outcomes


[PMID 19077707OA-icon.png] Pharmacogenetics of asthma.


[PMID 19665766OA-icon.png] Genetics and pharmacogenetics of the leukotriene pathway.


[PMID 20974993] Effect of citrus juice and SLCO2B1 genotype on the pharmacokinetics of montelukast.


GET Evidence
SLCO2B1-R312Q
aa_change Arg312Gln
aa_change_short R312Q
impact not reviewed
qualified_impact Insufficiently evaluated not reviewed
overall_frequency 0.0963004
summary



[PMID 23151832] SLCO2B1 c.935G>A single nucleotide polymorphism has no effect on the pharmacokinetics of montelukast and aliskiren


[PMID 23666051OA-icon.png] SLCO2B1 genetic polymorphisms in a Korean population: pyrosequencing analyses and comprehensive comparison with other populations.


[PMID 26668348] Association of SLCO2B1 Genotypes With Time to Progression and Overall Survival in Patients Receiving Androgen-Deprivation Therapy for Prostate Cancer.