Have questions? Visit https://www.reddit.com/r/SNPedia

rs1556314

From SNPedia

Orientationplus
Stabilizedplus
Make rs1556314(G;G)
Make rs1556314(G;T)
Make rs1556314(T;T)
ReferenceGRCh38 38.1/141
Chromosome21
Position44391460
GeneTRPM2
is asnp
is mentioned by
dbSNPrs1556314
ebirs1556314
HLIrs1556314
Exacrs1556314
Varsomers1556314
Maprs1556314
PheGenIrs1556314
hapmaprs1556314
1000 genomesrs1556314
hgdprs1556314
ensemblrs1556314
gopubmedrs1556314
geneviewrs1556314
scholarrs1556314
googlers1556314
pharmgkbrs1556314
gwascentralrs1556314
openSNPrs1556314
23andMers1556314
23andMe allrs1556314
SNP Nexus

SNPshotrs1556314
SNPdbers1556314
MSV3drs1556314
GWAS Ctlgrs1556314
GMAF0.2117
Max Magnitude
? (G;G) (G;T) (T;T) 28

[PMID 19133961] rs1556314 associated with bipolar disorder type I

  • C-T-A haplotype of SNPs rs1618355(C), rs933151(T), and rs749909(A) was significantly associated with early age at onset in BD-I families
OMIM125480
DescMAJOR AFFECTIVE DISORDER 1; MAFD1
Variant
Relatedalso
OMIM603749
DescTRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 2;
Variant
Relatedalso


[PMID 16205735] Fine mapping of a susceptibility locus for bipolar and genetically related unipolar affective disorders, to a region containing the C21ORF29 and TRPM2 genes on chromosome 21q22.3.


GET Evidence
TRPM2-D543E
aa_change Asp543Glu
aa_change_short D543E
impact not reviewed
qualified_impact Insufficiently evaluated not reviewed
overall_frequency 0.231549
summary