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rs1738074

From SNPedia

Orientationminus
Stabilizedminus
Make rs1738074(A;A)
Make rs1738074(A;G)
Make rs1738074(G;G)
ReferenceGRCh38 38.1/141
Chromosome6
Position159044945
GeneTAGAP
is asnp
is mentioned by
dbSNPrs1738074
ebirs1738074
HLIrs1738074
Exacrs1738074
Varsomers1738074
Maprs1738074
PheGenIrs1738074
hapmaprs1738074
1000 genomesrs1738074
hgdprs1738074
ensemblrs1738074
gopubmedrs1738074
geneviewrs1738074
scholarrs1738074
googlers1738074
pharmgkbrs1738074
gwascentralrs1738074
openSNPrs1738074
23andMers1738074
23andMe allrs1738074
SNP Nexus

SNPshotrs1738074
SNPdbers1738074
MSV3drs1738074
GWAS Ctlgrs1738074
GMAF0.4412
Max Magnitude
? (A;A) (A;G) (G;G) 28
GWAS
SNP rs1738074
PubMedID [PMID 18311140OA-icon.png]
Condition Celiac disease
Gene TAGAP
Risk Allele A
pValue 7.00E-008
OR 1.21
95% CI 1.13-1.30


OMIM612521
DescDIABETES MELLITUS, INSULIN-DEPENDENT, 21; IDDM21
Variant
Relatedalso
OMIM222100
DescDIABETES MELLITUS, INSULIN-DEPENDENT; IDDM
Variant
Relatedalso
OMIM612010
DescCELIAC DISEASE, SUSCEPTIBILITY TO, 12; CELIAC12
Variant
Relatedalso

[PMID 19693089] Four novel coeliac disease regions replicated in an association study of a Swedish-Norwegian family cohort


GWAS snp
PMID [PMID 20190752OA-icon.png]
Trait Celiac disease
Title Multiple common variants for celiac disease influencing immune gene expression
Risk Allele A
P-val 3E-15
Odds Ratio 1.16 [1.12-1.21]
GWAS snp
PMID [PMID 22190364OA-icon.png]
Trait
Title Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.
Risk Allele C
P-val 4E-7
Odds Ratio 1.1500 None
GWAS snp
PMID [PMID 21833088OA-icon.png]
Trait
Title Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.
Risk Allele G
P-val 7E-15
Odds Ratio 1.1300 [1.12-1.15]


[PMID 22087237OA-icon.png] Improving the estimation of celiac disease sibling risk by non-HLA genes


[PMID 22127930OA-icon.png] Association of single-nucleotide polymorphisms in CCR6, TAGAP, and TNFAIP3 with rheumatoid arthritis in African Americans

[PMID 18713140OA-icon.png] Translational mini-review series on the immunogenetics of gut disease: immunogenetics of coeliac disease.

[PMID 18853133OA-icon.png] Gene variants influencing measures of inflammation or predisposing to autoimmune and inflammatory diseases are not associated with the risk of type 2 diabetes.

[PMID 19073967OA-icon.png] Shared and distinct genetic variants in type 1 diabetes and celiac disease.

[PMID 21383967OA-icon.png] Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci.

[PMID 21390051OA-icon.png] Fine mapping the TAGAP risk locus in rheumatoid arthritis.


GET Evidence
rs1738074
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.460938
summary



[PMID 22592522] Association of celiac disease genes with inflammatory bowel disease in Finnish and Swedish patients.