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rs17561

From SNPedia

Orientationminus
Stabilizedminus
Make rs17561(G;G)
Make rs17561(G;T)
Make rs17561(T;T)
ReferenceGRCh38 38.1/141
Chromosome2
Position112779646
GeneIL1A
is asnp
is mentioned by
dbSNPrs17561
ebirs17561
HLIrs17561
Exacrs17561
Varsomers17561
Maprs17561
PheGenIrs17561
hapmaprs17561
1000 genomesrs17561
hgdprs17561
ensemblrs17561
gopubmedrs17561
geneviewrs17561
scholarrs17561
googlers17561
pharmgkbrs17561
gwascentralrs17561
openSNPrs17561
23andMers17561
23andMe allrs17561
SNP Nexus

SNPshotrs17561
SNPdbers17561
MSV3drs17561
GWAS Ctlgrs17561
GMAF0.2029
Max Magnitude
? (G;G) (G;T) (T;T) 28

[PMID 20157068] Association of IL1A, IL1B, and TNF Gene Polymorphisms With Chronic Rhinosinusitis With and Without Nasal Polyposis: A Replication Study


[PMID 22216303OA-icon.png] Functional Polymorphism of IL-1 Alpha and Its Potential Role in Obesity in Humans and Mice


[PMID 16642433OA-icon.png] Polymorphism in maternal LRP8 gene is associated with fetal growth.


[PMID 16820586OA-icon.png] Inflammatory gene polymorphisms and risk of postoperative myocardial infarction after cardiac surgery.


[PMID 16842617OA-icon.png] Interleukin gene polymorphisms and breast cancer: a case control study and systematic literature review.


[PMID 16918024] Association between the interleukin-1 family gene cluster and psoriatic arthritis.


[PMID 17327408OA-icon.png] Prognostic significance of host immune gene polymorphisms in follicular lymphoma survival.


[PMID 17665434OA-icon.png] Association of interleukin-6 and interleukin-10 genotypes with radiographic damage in rheumatoid arthritis is dependent on autoantibody status.


[PMID 17705862OA-icon.png] Optimization of candidate-gene SNP-genotyping by flexible oligonucleotide microarrays; analyzing variations in immune regulator genes of hay-fever samples.


[PMID 17932347] Polymorphisms in apoptosis- and proliferation-related genes, ionizing radiation exposure, and risk of breast cancer among U.S. Radiologic Technologists.


[PMID 18063673] Prospective meta-analysis of interleukin 1 gene complex polymorphisms confirms associations with ankylosing spondylitis.


[PMID 18454203OA-icon.png] Differential allelic expression in the human genome: a robust approach to identify genetic and epigenetic cis-acting mechanisms regulating gene expression.


[PMID 18576312OA-icon.png] A broad analysis of IL1 polymorphism and rheumatoid arthritis.


[PMID 18609743OA-icon.png] Genetics of psoriasis and psoriatic arthritis: update and future direction.


[PMID 18633131OA-icon.png] Host immune gene polymorphisms in combination with clinical and demographic factors predict late survival in diffuse large B-cell lymphoma patients in the pre-rituximab era.


[PMID 18676870OA-icon.png] Variants in inflammation genes and the risk of biliary tract cancers and stones: a population-based study in China.


[PMID 18727828OA-icon.png] Ischemic stroke risk, smoking, and the genetics of inflammation in a biracial population: the stroke prevention in young women study.


[PMID 18838388] Interleukin-1 promoter region polymorphism role in rheumatoid arthritis: a meta-analysis of IL-1B-511A/G variant reveals association with rheumatoid arthritis.


[PMID 18978339OA-icon.png] Large-scale evaluation of candidate genes identifies associations between DNA repair and genomic maintenance and development of benzene hematotoxicity.


[PMID 19035492OA-icon.png] Cytokine gene polymorphisms as risk and severity factors for juvenile dermatomyositis.


[PMID 19043479OA-icon.png] Association of -31T>C and -511 C>T polymorphisms in the interleukin 1 beta (IL1B) promoter in Korean keratoconus patients.


[PMID 19066394OA-icon.png] Organochlorine exposure, immune gene variation, and risk of non-Hodgkin lymphoma.


[PMID 19356949OA-icon.png] Cytokine SNPs: Comparison of allele frequencies by race and implications for future studies.


[PMID 19468064OA-icon.png] Parasites represent a major selective force for interleukin genes and shape the genetic predisposition to autoimmune conditions.


[PMID 19934104OA-icon.png] Radiographic severity of knee osteoarthritis is conditional on interleukin 1 receptor antagonist gene variations.


[PMID 20113413] Cytokine polymorphism in patients with migraine: some suggestive clues of migraine and inflammation.


[PMID 20192980] The interleukin-1 cluster gene region is associated with multiple sclerosis in an Italian Caucasian population.


[PMID 20459687OA-icon.png] Candidate malaria susceptibility/protective SNPs in hospital and population-based studies: the effect of sub-structuring.


[PMID 20725607OA-icon.png] CCL3 genotype and current depression increase risk of HIV-associated dementia.


[PMID 20811626OA-icon.png] Genetic variants in inflammation-related genes are associated with radiation-induced toxicity following treatment for non-small cell lung cancer.


[PMID 21279638] Coding single-nucleotide polymorphisms of interleukin-1 gene cluster are not associated with Kawasaki disease in the Korean population.


[PMID 21621860] Association of IL1A, IL1B, ILRN, IL6, IL10 and TNF-alpha polymorphisms with risk and clinical course of multiple sclerosis in a Polish population.


[PMID 22282663OA-icon.png] Ovarian cancer risk associated with inherited inflammation-related variants.


GET Evidence
IL1A-A114S
aa_change Ala114Ser
aa_change_short A114S
impact not reviewed
qualified_impact Insufficiently evaluated not reviewed
overall_frequency 0.259063
summary



[PMID 22723975OA-icon.png] Polymorphisms in RYBP and AOAH genes are associated with chronic rhinosinusitis in a Chinese population: a replication study


[PMID 23927441OA-icon.png] Genetic variants in IL1A and IL1B contribute to the susceptibility to 2009 pandemic H1N1 influenza A virus


[PMID 24272484OA-icon.png] Risk of Ovarian Cancer and the NF-κB Pathway: Genetic association with IL1A and TNFSF10


[PMID 21962386] The associations between interleukin-1 polymorphisms and susceptibility to ankylosing spondylitis: a meta-analysis.


[PMID 23459936OA-icon.png] Exploring the genetic basis of chronic periodontitis: a genome-wide association study.


[PMID 24862933] Association of an insertion/deletion polymorphism in IL1A 3'-UTR with risk for cervical carcinoma in Chinese Han Women


[PMID 25902400] Polymorphisms in the inflammatory pathway genes and the risk of preeclampsia in Sinhalese women


[PMID 26391153] Polymorphisms in host immune response associated genes and risk of nasopharyngeal carcinoma development in Portugal


[PMID 26448013OA-icon.png] High Incidence of Malaria Along the Sino-Burmese Border Is Associated With Polymorphisms of CR1, IL-1A, IL-4R, IL-4, NOS, and TNF, But Not With G6PD Deficiency


[PMID 24918527OA-icon.png] Genetic variations in IL1A and IL1RN are associated with the risk of preeclampsia in Chinese Han population