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rs17651507

From SNPedia

Orientationplus
Stabilizedplus
Make rs17651507(A;A)
Make rs17651507(A;T)
Make rs17651507(T;T)
ReferenceGRCh38 38.1/141
Chromosome17
Position45981644
GeneMAPT
is asnp
is mentioned by
dbSNPrs17651507
ebirs17651507
HLIrs17651507
Exacrs17651507
Varsomers17651507
Maprs17651507
PheGenIrs17651507
hapmaprs17651507
1000 genomesrs17651507
hgdprs17651507
ensemblrs17651507
gopubmedrs17651507
geneviewrs17651507
scholarrs17651507
googlers17651507
pharmgkbrs17651507
gwascentralrs17651507
openSNPrs17651507
23andMers17651507
23andMe allrs17651507
SNP Nexus

SNPshotrs17651507
SNPdbers17651507
MSV3drs17651507
GWAS Ctlgrs17651507
GMAF0.1561
Max Magnitude
? (A;A) (A;T) (T;T) 28
This SNP was identified as a "core" SNP helping to define one (of nine total) runs of homozygosity (ROH) potentially associated with increased risk for schizophrenia. Each region consists of at least 100 consecutive SNPs, generally spanning 500KB or more, for which both chromosomes in an individual were homozygous. The overall odds ratio for schizophrenia associated with inheriting 1, 2, or 3 of these 9 ROHs was calculated to be 3.3, 5.4, or 24, respectively, with 95% confidence intervals of (1.9-5.7), (3.7-16.1), and (6.9-83.9), respectively.[PMID 18077426OA-icon.png]

This particular SNP, rs17651507, was deemed to be the core SNP of a region on chromosome 17 with 211 SNPs spanning 1453KB from 17:141169023 to 17:42622984 (build 35). Potentially independent of the ROH, the risk allele for this SNP in the orientation as displayed in HapMap v21a is (T).[PMID 18077426OA-icon.png]