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rs1800544

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) 0
(G;G) 2 cognitive effects?
Make rs1800544(C;G)
ReferenceGRCh38 38.1/142
Chromosome10
Position111076745
GeneADRA2A
is asnp
is mentioned by
dbSNPrs1800544
ebirs1800544
HLIrs1800544
Exacrs1800544
Varsomers1800544
Maprs1800544
PheGenIrs1800544
hapmaprs1800544
1000 genomesrs1800544
hgdprs1800544
ensemblrs1800544
gopubmedrs1800544
geneviewrs1800544
scholarrs1800544
googlers1800544
pharmgkbrs1800544
gwascentralrs1800544
openSNPrs1800544
23andMers1800544
23andMe allrs1800544
SNP Nexus

SNPshotrs1800544
SNPdbers1800544
MSV3drs1800544
GWAS Ctlgrs1800544
GMAF0.4812
Max Magnitude2
rs1800544 (C-1291G) is a SNP located in the promoter region of ADRA2A (adrenergic receptor alpha 2A).

[PMID 17522710] GG genotype carriers had significantly higher consumption of sweet food products

[PMID 17894416] (Estonian Children Personality Behavior and Health Study subset, n = 419) GG genotype carriers had significantly higher scores on an assessment of depression, and significantly lower scores on morality and orderliness compared to CC carriers. girls with CC and CG genotypes scored higher than boys with the same genotypes on an assessment of extraversion. boys with GG genotypes, however, scored higher than girls with GG genotypes.

[PMID 10334470] GG genotype assoc. w/ higher scores of inattention

[PMID 19150055] Korean GG genotype carriers with ADHD had improved response to methylphenidate treatment

OMIM104210
DescALPHA-2A-ADRENERGIC RECEPTOR; ADRA2A
Variant
Relatedalso

[PMID 19604092] Association of the alpha2A adrenergic receptor -1291C/G polymorphism and antipsychotic-induced weight gain in European-Americans


[PMID 19922756] Effect of alpha(2A)-Adrenoceptor C-1291G Genotype and Maltreatment on Hyperactivity and Inattention in Adolescents


[PMID 16642439OA-icon.png] Cigarette smoking strongly modifies the association of LOC387715 and age-related macular degeneration.


[PMID 17512307OA-icon.png] Association analyses of adrenergic receptor polymorphisms with obesity and metabolic alterations.


[PMID 19258022OA-icon.png] Now or Later? An fMRI study of the effects of endogenous opioid blockade on a decision-making network.


[PMID 20864182] ADRA2A polymorphisms and ADHD in adults: possible mediating effect of personality.

Food Preference


[PMID 24166412] Alpha-2A adrenergic receptor gene variants are associated with increased intra-individual variability in response time


[PMID 22940547] Preliminary evidence for association between schizophrenia and polymorphisms in the regulatory Regions of the ADRA2A, DRD3 and SNAP-25 Genes.


[PMID 23266789] Adrenergic neurotransmitter system transporter and receptor genes associated with atomoxetine response in attention-deficit hyperactivity disorder children.


[PMID 23808549OA-icon.png] Candidate gene associations with withdrawn behavior.


[PMID 25163438] Polymorphism in alpha 2A adrenergic receptor gene is associated with sialorrhea in schizophrenia patients on clozapine treatment


[PMID 25818344OA-icon.png] ADRA2A is involved in neuro-endocrine regulation of bone resorption


[PMID 25854875] Catecholamine pathway polymorphisms and antidepressant response


[PMID 26410938] [Genetic Association of ADRA2A and ADRB3 Genes with Metabolic Syndrome among the Tatars]


[PMID 26563278] ADRA2A Germline Gene Polymorphism is Associated to the Severity, but not to the Risk, of Breast Cancer


[PMID 26832728] Genotyping of single nucleotide polymorphisms related to attention-deficit hyperactivity disorder.