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rs1883025

From SNPedia

Orientationminus
Stabilizedminus
Make rs1883025(A;A)
Make rs1883025(A;G)
Make rs1883025(G;G)
ReferenceGRCh38 38.1/141
Chromosome9
Position104902020
GeneABCA1
is asnp
is mentioned by
dbSNPrs1883025
ebirs1883025
HLIrs1883025
Exacrs1883025
Varsomers1883025
Maprs1883025
PheGenIrs1883025
hapmaprs1883025
1000 genomesrs1883025
hgdprs1883025
ensemblrs1883025
gopubmedrs1883025
geneviewrs1883025
scholarrs1883025
googlers1883025
pharmgkbrs1883025
gwascentralrs1883025
openSNPrs1883025
23andMers1883025
23andMe allrs1883025
SNP Nexus

SNPshotrs1883025
SNPdbers1883025
MSV3drs1883025
GWAS Ctlgrs1883025
GMAF0.2815
Max Magnitude
? (A;A) (A;G) (G;G) 28
GWAS snp
PMID [PMID 19060906OA-icon.png]
Trait HDL cholesterol
Title Common variants at 30 loci contribute to polygenic dyslipidemia
Risk Allele T
P-val 1E-9
Odds Ratio 0.08 [0.04-0.12] SD decrease


OMIM600046
Desc
Variant
Relatedalso
[PMID 21738485OA-icon.png] Genetic determinants of lipid traits in diverse populations from the population architecture using genomics and epidemiology (PAGE) study
GWAS snp
PMID [PMID 20686565OA-icon.png]
Trait
Title Biological, clinical and population relevance of 95 loci for blood lipids.
Risk Allele T
P-val 2E-33
Odds Ratio 0.9400 None


[PMID 22247473OA-icon.png] Prospective assessment of genetic effects on progression to different stages of age-related macular degeneration using multistate Markov models

GWAS snp
PMID [PMID 22399527OA-icon.png]
Trait
Title Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits.
Risk Allele T
P-val 6E-10
Odds Ratio 0.1000 None

[PMID 17430597OA-icon.png] Apolipoprotein E levels in cerebrospinal fluid and the effects of ABCA1 polymorphisms.

[PMID 19951432OA-icon.png] Analysis of recently identified dyslipidemia alleles reveals two loci that contribute to risk for carotid artery disease.

[PMID 20160193OA-icon.png] Investigation of variants identified in caucasian genome-wide association studies for plasma high-density lipoprotein cholesterol and triglycerides levels in Mexican dyslipidemic study samples.

[PMID 20339536OA-icon.png] Genome-wide association of lipid-lowering response to statins in combined study populations.

[PMID 20385819OA-icon.png] Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration.

[PMID 20385826OA-icon.png] Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC).


GET Evidence
rs1883025
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.309524
summary



[PMID 24223199OA-icon.png] Association of HDL-Related Loci with Age-Related Macular Degeneration and Plasma Lutein and Zeaxanthin: the Alienor Study


[PMID 24970616] The contribution of genetic factors to phenotype and progression of drusen in early age-related macular degeneration

GWAS snp
PMID [PMID 24097068OA-icon.png]
Trait Cholesterol, total
Title Discovery and refinement of loci associated with lipid levels.
Risk Allele T
P-val 6E-53
Odds Ratio .07 [NR] unit decrease