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rs2119783

From SNPedia

Orientationminus
Stabilizedminus
Make rs2119783(A;A)
Make rs2119783(A;G)
Make rs2119783(G;G)
ReferenceGRCh38 38.1/141
Chromosome8
Position57029799
is asnp
is mentioned by
dbSNPrs2119783
ebirs2119783
HLIrs2119783
Exacrs2119783
Varsomers2119783
Maprs2119783
PheGenIrs2119783
hapmaprs2119783
1000 genomesrs2119783
hgdprs2119783
ensemblrs2119783
gopubmedrs2119783
geneviewrs2119783
scholarrs2119783
googlers2119783
pharmgkbrs2119783
gwascentralrs2119783
openSNPrs2119783
23andMers2119783
23andMe allrs2119783
SNP Nexus

SNPshotrs2119783
SNPdbers2119783
MSV3drs2119783
GWAS Ctlgrs2119783
GMAF0.4803
Max Magnitude
? (A;A) (A;G) (G;G) 28

This SNP was identified as a "core" SNP helping to define one (of nine total) runs of homozygosity (ROH) potentially associated with increased risk for schizophrenia. Each region consists of at least 100 consecutive SNPs, generally spanning 500KB or more, for which both chromosomes in an individual were homozygous. The overall odds ratio for schizophrenia associated with inheriting 1, 2, or 3 of these 9 ROHs was calculated to be 3.3, 5.4, or 24, respectively, with 95% confidence intervals of (1.9-5.7), (3.7-16.1), and (6.9-83.9), respectively.[PMID 18077426OA-icon.png]

This particular SNP, rs2119783, was deemed to be the core SNP of a region on chromosome 8 with 120 SNPs spanning 627KB from 8:57989122 to 8:58616467 (build 35). Potentially independent of the ROH, the risk allele for this SNP in the orientation as displayed in HapMap v21a is (G).[PMID 18077426OA-icon.png]