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AA and Longevity[edit]

Not so sure the AA genotype should be marked as negative. Lower IGF1 levels have been associated with longevity in several studies. See, for ex:


--User:Epsilon4 2016-02-3 19:08 (UTC) 19:08, 3 February 2016 (UTC)

Agreed. The evidence is relatively weak, but it is positive, and the A allele has been associated with both increased, and decreased, risk of some cancers (but in small studies). Might as well say that, and keep the repute neutral. Greg (talk) 00:01, 4 February 2016 (UTC)