|(A;A)||2.1||Lower IGF-1 levels; some reported associations with longevity as well as certain cancers|
|(G;G)||1.1||Normal IGF-1 level|
[PMID 19460140] A polymorphic variant of the insulin-like growth factor 1 (IGF-1) receptor correlates with male longevity in the Italian population: a genetic study and evaluation of circulating IGF-1 from the "Treviso Longeva (TRELONG)" study
[PMID 22115178] Insulin-like growth factor 1 receptor polymorphism rs2229765 and circulating interleukin-6 level affect male longevity in a population-based prospective study (Treviso Longeva- TRELONG)
[PMID 19124506] Common genetic variation in candidate genes and susceptibility to subtypes of breast cancer.
[PMID 19124510] Insulin-like growth factor-1- and interleukin-6-related gene variation and risk of multiple myeloma.
[PMID 19877134] Sequence variation in IGF1R is associated with differences in insulin levels in nondiabetic Old Order Amish.
[PMID 20302654] Genotypes and haplotypes in the insulin-like growth factors, their receptors and binding proteins in relation to plasma metabolic levels and mammographic density.
[PMID 20625407] A comprehensive in silico analysis of the functional and structural impact of SNPs in the IGF1R gene.
[PMID 21047277] Polymorphisms of insulin-like growth factor-1 (IGF-1) and IGF-1 receptor (IGF-1R) contribute to pathologic progression in childhood IgA nephropathy.
[PMID 21304894] Mapping a new spontaneous preterm birth susceptibility gene, IGF1R, using linkage, haplotype sharing, and association analysis.
[PMID 24350933] Association Between Genetic Variations In The Insulin/Insulin-Like Growth Factor (Igf-1) Signaling Pathway And Longevity: A Systematic Review And Meta-Analysis
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[PMID 25189651] Association of insulin-like growth factor-I receptor polymorphism with colorectal cancer development
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