rs1322784
From SNPedia
| Orientation | minus |
| Stabilized | minus |
| Make rs1322784(C;C) |
| Make rs1322784(C;T) |
| Make rs1322784(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 1 |
| Position | 231793189 |
| Gene | DISC1, TSNAX-DISC1 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs1322784 |
| dbSNP (classic) | rs1322784 |
| ClinGen | rs1322784 |
| ebi | rs1322784 |
| HLI | rs1322784 |
| Exac | rs1322784 |
| Gnomad | rs1322784 |
| Varsome | rs1322784 |
| LitVar | rs1322784 |
| Map | rs1322784 |
| PheGenI | rs1322784 |
| Biobank | rs1322784 |
| 1000 genomes | rs1322784 |
| hgdp | rs1322784 |
| ensembl | rs1322784 |
| geneview | rs1322784 |
| scholar | rs1322784 |
| rs1322784 | |
| pharmgkb | rs1322784 |
| gwascentral | rs1322784 |
| openSNP | rs1322784 |
| 23andMe | rs1322784 |
| SNPshot | rs1322784 |
| SNPdbe | rs1322784 |
| MSV3d | rs1322784 |
| GWAS Ctlg | rs1322784 |
| GMAF | 0.3039 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
rs1322784, an intragenic SNP associated with the 'disrupted in schizophrenia' DISC1 gene, was reported to be associated with asperger's syndrome [PMID 17579608]
This same study also implicated the "HEP3 haplotype" in asperger's syndrome. The HEP3 haplotype contains two SNPs in the DISC1 gene, rs751229 and rs3738401, and was first reported as a haplotype under-represented in individuals with affective disorders. [PMID 14532331, PMID 15386212]
[PMID 19414483
] The DISC locus and schizophrenia: evidence from an association study in a central European sample and from a meta-analysis across different European populations.
