rs1334512

plus

Geno	Mag	Summary
(G;G)		0.37x decreased risk for severe malaria
(G;T)		decreased risk for severe malaria
(T;T)		normal

Reference

GRCh38 38.1/141

Chromosome

7

Position

80638588

Gene

CD36

is a	snp
is	mentioned by
dbSNP	rs1334512
dbSNP (classic)	rs1334512
ClinGen	rs1334512
ebi	rs1334512
HLI	rs1334512
Exac	rs1334512
Gnomad	rs1334512
Varsome	rs1334512
LitVar	rs1334512
Map	rs1334512
PheGenI	rs1334512
Biobank	rs1334512
1000 genomes	rs1334512
hgdp	rs1334512
ensembl	rs1334512
geneview	rs1334512
scholar	rs1334512
google	rs1334512
pharmgkb	rs1334512
gwascentral	rs1334512
openSNP	rs1334512
23andMe	rs1334512
SNPshot	rs1334512
SNPdbe	rs1334512
MSV3d	rs1334512
GWAS Ctlg	rs1334512

GMAF

0.2741

Max Magnitude

0

rs1334512, also known as -53, is a SNP in the CD36 molecule (thrombospondin receptor) CD36 gene.

A study of 552 individuals in India found a protective association between the rs1334512(T) allele and the (T;T) genotype related to severe malaria; (T;T) homozgyotes had a 0.37x (p = 0.004)decreased risk compared to (G;G) homozygotes.[1]

[PMID 17705862 ] Optimization of candidate-gene SNP-genotyping by flexible oligonucleotide microarrays; analyzing variations in immune regulator genes of hay-fever samples.

[PMID 19055786 ] Variations in host genes encoding adhesion molecules and susceptibility to falciparum malaria in India.