rs1417066
From SNPedia
| Orientation | minus |
| Stabilized | minus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 1 | risk of osteoarthritis |
| (C;T) | 1 | slightly increased risk of osteoarthritis |
| Make rs1417066(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 1 |
| Position | 219500486 |
| Gene | LOC102723886, LOC107985272 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs1417066 |
| dbSNP (classic) | rs1417066 |
| ClinGen | rs1417066 |
| ebi | rs1417066 |
| HLI | rs1417066 |
| Exac | rs1417066 |
| Gnomad | rs1417066 |
| Varsome | rs1417066 |
| LitVar | rs1417066 |
| Map | rs1417066 |
| PheGenI | rs1417066 |
| Biobank | rs1417066 |
| 1000 genomes | rs1417066 |
| hgdp | rs1417066 |
| ensembl | rs1417066 |
| geneview | rs1417066 |
| scholar | rs1417066 |
| rs1417066 | |
| pharmgkb | rs1417066 |
| gwascentral | rs1417066 |
| openSNP | rs1417066 |
| 23andMe | rs1417066 |
| SNPshot | rs1417066 |
| SNPdbe | rs1417066 |
| MSV3d | rs1417066 |
| GWAS Ctlg | rs1417066 |
| GMAF | 0.371 |
| Max Magnitude | 1 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
[PMID 22763110
] A 2012 large study of osteoarthritis was replicated in 7473 cases and 42,938 controls. The meta-analysis (prior to replication) found approximately 1.12x risk of osteoarthritis for minor allele of rs1417066 (as shown in table ST4, appendix, p. 76), but its significance was p=3·90 E-06 and it did not reach the minimum for genome-wide significance at (p=5·0×10−8).
| GWAS snp | |
|---|---|
| PMID | [PMID 22763110]
|
| Trait | Osteoarthritis |
| Title | Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study. |
| Risk Allele | G |
| P-val | 1E-6 |
| Odds Ratio | 1.07 [1.04-1.10] |
