rs1800469(C;T)
From SNPedia
| slightly higher TGF-β1 levels, higher risk for COPD? |
| Is a | genotype |
| of | rs1800469 |
| Gene | TGFB1, B9D2 |
| Chromosome | 19 |
| Position | 41,354,391 |
| mentioned | by |
| Magnitude | 1 |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 1 | lower TGF-β1 levels, higher risk for COPD? |
| (C;T) | 1 | slightly higher TGF-β1 levels, higher risk for COPD? |
| (T;T) | 1 | higher TGF-β1 levels |
The T version, which this (C;T) has one of, increases TGF-β1 levels by preventing AP1 from downregulating TGF-β1 production. But it won't be as high as in the rarer T;T combination.
