rs1800932

Orientation

plus

Stabilized

plus

Geno	Mag	Summary
(A;A)	0	common in clinvar

Make rs1800932(A;G)

Make rs1800932(G;G)

Reference

GRCh38 38.1/141

Chromosome

2

Position

47790942

Gene

MSH6

is a	snp
is	mentioned by
dbSNP	rs1800932
dbSNP (classic)	rs1800932
ClinGen	rs1800932
ebi	rs1800932
HLI	rs1800932
Exac	rs1800932
Gnomad	rs1800932
Varsome	rs1800932
LitVar	rs1800932
Map	rs1800932
PheGenI	rs1800932
Biobank	rs1800932
1000 genomes	rs1800932
hgdp	rs1800932
ensembl	rs1800932
geneview	rs1800932
scholar	rs1800932
google	rs1800932
pharmgkb	rs1800932
gwascentral	rs1800932
openSNP	rs1800932
23andMe	rs1800932
SNPshot	rs1800932
SNPdbe	rs1800932
MSV3d	rs1800932
GWAS Ctlg	rs1800932

GMAF

0.1042

Max Magnitude

0

?	(A;A) (A;G) (G;G)	28

[PMID 20149637] Common variants in human CRC genes as low-risk alleles

ClinVar
Risk	rs1800932(G;G)
Alt	rs1800932(G;G)
Reference	Rs1800932(A;A)
Significance	Non-pathogenic
Disease	Lynch syndrome not specified Hereditary cancer-predisposing syndrome
Variation	info
Gene	MSH6
CLNDBN	Lynch syndrome not specified Hereditary cancer-predisposing syndrome
Reversed	0
HGVS	NC_000002.11:g.48018081A>G
CLNSRC	International Society for Gastrointestinal Hereditary Tumours
CLNACC	RCV000030265.4, RCV000035321.8, RCV000162362.1,

[PMID 20386703] Association between DNA damage response and repair genes and risk of invasive serous ovarian cancer.

[PMID 10537275] Germ-line msh6 mutations in colorectal cancer families.

[PMID 15805151] No MSH6 germline mutations in breast cancer families with colorectal and/or endometrial cancer.

[PMID 24357391] DNA mismatch repair gene MSH6 implicated in determining age at natural menopause