rs1805017
From SNPedia
| Orientation | minus |
| Stabilized | minus |
| Geno | Mag | Summary |
|---|---|---|
| (G;G) | 0 | common in clinvar |
| Make rs1805017(A;A) |
| Make rs1805017(A;G) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 6 |
| Position | 46716485 |
| Gene | PLA2G7 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs1805017 |
| dbSNP (classic) | rs1805017 |
| ClinGen | rs1805017 |
| ebi | rs1805017 |
| HLI | rs1805017 |
| Exac | rs1805017 |
| Gnomad | rs1805017 |
| Varsome | rs1805017 |
| LitVar | rs1805017 |
| Map | rs1805017 |
| PheGenI | rs1805017 |
| Biobank | rs1805017 |
| 1000 genomes | rs1805017 |
| hgdp | rs1805017 |
| ensembl | rs1805017 |
| geneview | rs1805017 |
| scholar | rs1805017 |
| rs1805017 | |
| pharmgkb | rs1805017 |
| gwascentral | rs1805017 |
| openSNP | rs1805017 |
| 23andMe | rs1805017 |
| SNPshot | rs1805017 |
| SNPdbe | rs1805017 |
| MSV3d | rs1805017 |
| GWAS Ctlg | rs1805017 |
| GMAF | 0.2525 |
| Max Magnitude | 0 |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
|
| ||
| GWAS snp | |
|---|---|
| PMID | [PMID 20442857 ]
|
| Trait | Lipoprotein-associated phospholipase A2 activity and mass |
| Title | Genome-wide association study of Lp-PLA(2) activity and mass in the Framingham Heart Study |
| Risk Allele | T |
| P-val | 6E-14 |
| Odds Ratio | 11.10 [NR] ng/mL increase |
| GWAS snp | |
|---|---|
| PMID | [PMID 22003152]
|
| Trait | |
| Title | Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies. |
| Risk Allele | T |
| P-val | 2E-23 |
| Odds Ratio | 0.0430 None |
[PMID 18204052] Comprehensive genetic analysis of the platelet activating factor acetylhydrolase (PLA2G7) gene and cardiovascular disease in case-control and family datasets.
[PMID 23404648] An association study between genetic polymorphisms related to lipoprotein-associated phospholipase A(2) and coronary heart disease
| ClinVar | |
|---|---|
| Risk | rs1805017(A;A) |
| Alt | rs1805017(A;A) |
| Reference | Rs1805017(G;G) |
| Significance | Untested |
| Disease | not provided |
| Variation | info |
| Gene | PLA2G7 |
| CLNDBN | not provided |
| Reversed | 1 |
| HGVS | NC_000006.11:g.46684222C>T |
| CLNSRC | UniProtKB (protein) |
| CLNACC | RCV000049573.1, |
[PMID 24732951] Lipoprotein-associated phospholipase A2 single-nucleotide polymorphisms and cardiovascular events in patients with coronary artery disease
[PMID 29728838] Interaction between nonsynonymous polymorphisms in PLA2G7 gene and smoking on the risk of coronary heart disease in a Chinese population.
