rs2233434
From SNPedia
| Orientation | minus |
| Stabilized | minus |
| Geno | Mag | Summary |
|---|---|---|
| (T;T) | 0 | common in complete genomics |
| Make rs2233434(C;C) |
| Make rs2233434(C;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 6 |
| Position | 44265183 |
| Gene | NFKBIE |
| is a | snp |
| is | mentioned by |
| dbSNP | rs2233434 |
| dbSNP (classic) | rs2233434 |
| ClinGen | rs2233434 |
| ebi | rs2233434 |
| HLI | rs2233434 |
| Exac | rs2233434 |
| Gnomad | rs2233434 |
| Varsome | rs2233434 |
| LitVar | rs2233434 |
| Map | rs2233434 |
| PheGenI | rs2233434 |
| Biobank | rs2233434 |
| 1000 genomes | rs2233434 |
| hgdp | rs2233434 |
| ensembl | rs2233434 |
| geneview | rs2233434 |
| scholar | rs2233434 |
| rs2233434 | |
| pharmgkb | rs2233434 |
| gwascentral | rs2233434 |
| openSNP | rs2233434 |
| 23andMe | rs2233434 |
| SNPshot | rs2233434 |
| SNPdbe | rs2233434 |
| MSV3d | rs2233434 |
| GWAS Ctlg | rs2233434 |
| GMAF | 0.07392 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
| GWAS snp | |
|---|---|
| PMID | [PMID 22446963] |
| Trait | |
| Title | Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population. |
| Risk Allele | G |
| P-val | 6E-19 |
| Odds Ratio | 1.1900 None |
| GWAS snp | |
|---|---|
| PMID | [PMID 23028356 ]
|
| Trait | Rheumatoid arthritis |
| Title | Functional variants in NFKBIE and RTKN2 involved in activation of the NF-κB pathway are associated with rheumatoid arthritis in Japanese. |
| Risk Allele | G |
| P-val | 1E-15 |
| Odds Ratio | 1.20 [1.15-1.26] |
[PMID 26587663] Impaired NFKBIE Gene Function decreases Cellular Uptake of Methotrexate by Down-regulating SLC19A1 Expression in a Human Rheumatoid Arthritis Cell Line
