rs2239633
May influence risk of childhood B-cell acute lymphoblastic leukemia |
Orientation | minus |
Stabilized | minus |
Geno | Mag | Summary |
---|---|---|
(C;C) |
Make rs2239633(C;T) |
Make rs2239633(T;T) |
Reference | GRCh38 38.1/141 |
Chromosome | 14 |
Position | 23119848 |
Gene | CEBPE |
is a | snp |
is | mentioned by |
dbSNP | rs2239633 |
dbSNP (classic) | rs2239633 |
ClinGen | rs2239633 |
ebi | rs2239633 |
HLI | rs2239633 |
Exac | rs2239633 |
Gnomad | rs2239633 |
Varsome | rs2239633 |
LitVar | rs2239633 |
Map | rs2239633 |
PheGenI | rs2239633 |
Biobank | rs2239633 |
1000 genomes | rs2239633 |
hgdp | rs2239633 |
ensembl | rs2239633 |
geneview | rs2239633 |
scholar | rs2239633 |
rs2239633 | |
pharmgkb | rs2239633 |
gwascentral | rs2239633 |
openSNP | rs2239633 |
23andMe | rs2239633 |
SNPshot | rs2239633 |
SNPdbe | rs2239633 |
MSV3d | rs2239633 |
GWAS Ctlg | rs2239633 |
GMAF | 0.3848 |
Max Magnitude | 0 |
? | (C;C) (C;T) (T;T) | 28 |
---|---|---|
|
GWAS snp | |
---|---|
PMID | [PMID 19684604] |
Trait | Acute lymphoblastic leukemia (childhood) |
Title | Loci on 7p12.2, 10q21.2 and 14q11.2 are associated with risk of childhood acute lymphoblastic leukemia |
Risk Allele | G |
P-val | 3E-7 |
Odds Ratio | 1.34 [1.22-1.45] |
[PMID 22422485] Genetic variants modify susceptibility to leukemia in infants: A Children's Oncology Group report
[PMID 20919861] Variation at 7p12.2 and 10q21.2 influences childhood acute lymphoblastic leukemia risk in the Thai population and may contribute to racial differences in leukemia incidence.
[PMID 24564228] ARID5B polymorphism confers an increased risk to acquire specific MLL rearrangements in early childhood leukemia
GWAS snp | |
---|---|
PMID | [PMID 23996088] |
Trait | Acute lymphoblastic leukemia (B-cell precursor) |
Title | Variation at 10p12.2 and 10p14 influences risk of childhood B-cell acute lymphoblastic leukemia and phenotype. |
Risk Allele | |
P-val | 1E-16 |
Odds Ratio | NR NR |
[PMID 26177813] Replication analysis confirms the association of several variants with acute myeloid leukemia in Chinese population
[PMID 26388693] A common genetic variation in CEBPE and acute lymphoblastic leukemia: a meta-analysis of the available evidence
[PMID 26575185] Somatic Mutation Allelic Ratio Test Using ddPCR (SMART-ddPCR): An Accurate Method for Assessment of Preferential Allelic Imbalance in Tumor DNA
[PMID 27279837] Analysis of possible genetic risk factors contributing to development of childhood acute lymphoblastic leukaemia in the Latvian population.
[PMID 28768142] Contributions of IKZF1, DDC, CDKN2A, CEBPE, and LMO1 Gene Polymorphisms to Acute Lymphoblastic Leukemia in a Yemeni Population.