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rs2908004

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(C;C) 2 weaker bones
(T;T) 2 stronger bones
Make rs2908004(C;T)
ReferenceGRCh38 38.1/141
Chromosome7
Position121329715
GeneWNT16
is asnp
is mentioned by
dbSNPrs2908004
dbSNP (classic)rs2908004
ClinGenrs2908004
ebirs2908004
HLIrs2908004
Exacrs2908004
Gnomadrs2908004
Varsomers2908004
LitVarrs2908004
Maprs2908004
PheGenIrs2908004
Biobankrs2908004
1000 genomesrs2908004
hgdprs2908004
ensemblrs2908004
geneviewrs2908004
scholarrs2908004
googlers2908004
pharmgkbrs2908004
gwascentralrs2908004
openSNPrs2908004
23andMers2908004
SNPshotrs2908004
SNPdbers2908004
MSV3drs2908004
GWAS Ctlgrs2908004
GMAF0.4793
Max Magnitude2
? (C;C) (C;T) (T;T) 28


[PMID 22792071OA-icon.png] WNT16 Influences Bone Mineral Density, Cortical Bone Thickness, Bone Strength, and Osteoporotic Fracture Risk


[PMID 23417354] Missense polymorphisms of the WNT16 gene are associated with bone mass, hip geometry and fractures.

Osteoporosis

GWAS snp
PMID [PMID 24945404OA-icon.png]
Trait Bone mineral density (paediatric, lower limb)
Title Phenotypic dissection of bone mineral density reveals skeletal site specificity and facilitates the identification of novel loci in the genetic regulation of bone mass attainment.
Risk Allele A
P-val 3E-11
Odds Ratio .10 [0.071-0.129] unit increase


[PMID 31560818OA-icon.png] Variations of Wnt/β-catenin pathway-related genes in susceptibility to knee osteoarthritis: A three-centre case-control study.