rs312481

Orientation

minus

Stabilized

minus

Geno	Mag	Summary
(C;C)	0	better response to certain calcium channel blockers
(C;T)	0	normal
(T;T)		normal

Reference

GRCh38 38.1/141

Chromosome

3

Position

53517875

Gene

CACNA1D

is a	snp
is	mentioned by
dbSNP	rs312481
dbSNP (classic)	rs312481
ClinGen	rs312481
ebi	rs312481
HLI	rs312481
Exac	rs312481
Gnomad	rs312481
Varsome	rs312481
LitVar	rs312481
Map	rs312481
PheGenI	rs312481
Biobank	rs312481
1000 genomes	rs312481
hgdp	rs312481
ensembl	rs312481
geneview	rs312481
scholar	rs312481
google	rs312481
pharmgkb	rs312481
gwascentral	rs312481
openSNP	rs312481
23andMe	rs312481
SNPshot	rs312481
SNPdbe	rs312481
MSV3d	rs312481
GWAS Ctlg	rs312481

GMAF

0.1823

Max Magnitude

0

?	(C;C) (C;T) (T;T)	28

rs312481 is a SNP in the calcium channel, voltage-dependent, L type, alpha 1D subunit CACNA1D gene.

A study of 161 Japanese patients (85 men, 76 women) being treated for hypertension with L-type dCCBs (calcium channel blockers) concluded that individuals with rs312481(C;C) genotypes responded better, as measured by lowered systolic and diastolic blood pressure readings.[PMID 19225208]