Geno
|
Mag
|
Summary
|
(A;A)
|
2
|
lower HDL cholesterol
|
(A;G)
|
|
lower HDL cholesterol
|
(G;G)
|
|
normal risk
|
The (A) allele of rs326 was associated with risk for lower high-density lipoprotein (HDL) cholesterol plasma levels in 3 independent population samples, including both Caucasians and African-Americans.[PMID 17952847]
GWAS snp
|
PMID
|
[PMID 18193046]
|
Trait
|
Triglycerides
|
Title
|
Genome-wide scan identifies variation in MLXIPL associated with plasma triglycerides
|
Risk Allele
|
A
|
P-val
|
4.9999999999999997E-12
|
Odds Ratio
|
6.60 [3.66-9.54] % higher
|
[PMID 21149302] Effects of genetic variants on lipid parameters and dyslipidemia in a Chinese population
[PMID 15980532] SOP3v2: web-based selection of oligonucleotide primer trios for genotyping of human and mouse polymorphisms.
[PMID 19041386] Genetic-epidemiological evidence on genes associated with HDL cholesterol levels: a systematic in-depth review.
[PMID 20150529] Associations of lipoprotein lipase gene polymorphisms with longitudinal plasma lipid trends in young adults: The Coronary Artery Risk Development in Young Adults (CARDIA) study.
GWAS snp
|
PMID
|
[PMID 23726366]
|
Trait
|
Triglycerides
|
Title
|
Genome-wide Characterization of Shared and Distinct Genetic Components that Influence Blood Lipid Levels in Ethnically Diverse Human Populations.
|
Risk Allele
|
T
|
P-val
|
1E-8
|
Odds Ratio
|
.04 [NR] unit decrease
|