rs4220
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (G;G) | 0 | common in clinvar |
| Make rs4220(A;A) |
| Make rs4220(A;G) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 4 |
| Position | 154570607 |
| Gene | FGB |
| is a | snp |
| is | mentioned by |
| dbSNP | rs4220 |
| dbSNP (classic) | rs4220 |
| ClinGen | rs4220 |
| ebi | rs4220 |
| HLI | rs4220 |
| Exac | rs4220 |
| Gnomad | rs4220 |
| Varsome | rs4220 |
| LitVar | rs4220 |
| Map | rs4220 |
| PheGenI | rs4220 |
| Biobank | rs4220 |
| 1000 genomes | rs4220 |
| hgdp | rs4220 |
| ensembl | rs4220 |
| geneview | rs4220 |
| scholar | rs4220 |
| rs4220 | |
| pharmgkb | rs4220 |
| gwascentral | rs4220 |
| openSNP | rs4220 |
| 23andMe | rs4220 |
| SNPshot | rs4220 |
| SNPdbe | rs4220 |
| MSV3d | rs4220 |
| GWAS Ctlg | rs4220 |
| GMAF | 0.1726 |
| Max Magnitude | 0 |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
|
| ||
[PMID 20135074] A genetic variant in the gene encoding fibrinogen beta chain predicted development of hypertension in Chinese men
[PMID 20167083
] Fibrinogen beta variants confer protection against coronary artery disease in a Greek case-control study
| ClinVar | |
|---|---|
| Risk | rs4220(A;A) |
| Alt | rs4220(A;A) |
| Reference | Rs4220(G;G) |
| Significance | Other |
| Disease | FIBRINOGEN BALTIMORE 2 not specified Afibrinogenemia |
| Variation | info |
| Gene | FGB |
| CLNDBN | FIBRINOGEN BALTIMORE 2 not specified Afibrinogenemia, congenital |
| Reversed | 0 |
| HGVS | NC_000004.11:g.155491759G>A |
| CLNSRC | OMIM Allelic Variant UniProtKB (protein) |
| CLNACC | RCV000017808.1, RCV000244462.1, RCV000285950.1, |
[PMID 19064790] Predictive genomics of cardioembolic stroke.
[PMID 20031577] Novel loci, including those related to Crohn disease, psoriasis, and inflammation, identified in a genome-wide association study of fibrinogen in 17 686 women: the Women's Genome Health Study.
[PMID 20388367] [Polymorphisms of vascular diseases-related genes in Guangzhou Biobank Cohort Study].
[PMID 21258858] Genetic associations between fibrinogen and cognitive performance in three Scottish cohorts.
[PMID 22116284] A two-step genetic study on quantitative precursors of coronary artery disease in a homogeneous Indian population: case-control association discovery and validation by transmission-disequilibrium test.
[PMID 22273812] Replication and characterisation of genetic variants in the fibrinogen gene cluster with plasma fibrinogen levels and haematological traits in the Third National Health and Nutrition Examination Survey.
[PMID 23220916] Elevated fibrinogen levels are associated with risk of pulmonary embolism, but not with deep venous thrombosis.
[PMID 32214403] Evaluation of single nucleotide polymorphisms in 6 candidate genes and carotid intima-media thickness in community-dwelling residents.
